ArticleClinical and translational radiation oncology2018
The posterior cerebellum, a new organ at risk?
Article in Clinical and translational radiation oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Hippocampal radiotherapy dose constraints for predicting long-term neurocognitive outcomes: mature data from a prospective trial in young patients with brain tumors.Neuro-oncology · 2020Trial
- Clinical advances and challenges in dose constraints for organs at risk in proton therapy: A systematic review of the last decade's literature.Precision radiation oncology · 2025Review
- The effect of radiation dose to the brain on early self-reported cognitive function in brain and head-and-neck cancer patients.Clinical and translational radiation oncology · 2025Article
- Increased functional network segregation in glioma patients posttherapy: A neurological compensatory response or catastrophe for cognition?Network neuroscience (Cambridge, Mass.) · 2025Article
- Neural Pathways Linking Autonomous Exercise Motivation and Exercise-Induced Unhealthy Eating: A Resting-State fMRI Study.Brain sciences · 2024Article
- Clinical implementation of standardized neurocognitive assessment before and after radiation to the brain.Clinical and translational radiation oncology · 2023Article
- Neurocognition and mean radiotherapy dose to vulnerable brain structures: new organs at risk?Radiation oncology (London, England) · 2023Article
- Cerebellar irradiation does not cause hyperactivity, fear, and anxiety-related disorders in the juvenile rat brain.European radiology experimental · 2022Article
- Comprehensive and clinically accurate head and neck cancer organs-at-risk delineation on a multi-institutional study.Nature communications · 2022Article
- Significant Structural Alterations and Functional Connectivity Alterations of Cerebellar Gray Matter in Patients With Somatic Symptom Disorder.Frontiers in neuroscience · 2022Article
- The ROCOCO performance scoring system translates dosimetric differences into clinically relevant endpoints: Comparing IMPT to VMAT in an example pilocytic astrocytoma dataset.Clinical and translational radiation oncology · 2021Article
- Regular Tai Chi Practice Is Associated With Improved Memory as Well as Structural and Functional Alterations of the Hippocampus in the Elderly.Frontiers in aging neuroscience · 2020Article
- Age-related differences in brain activations during spatial memory formation in a well-learned virtual Morris water maze (vMWM) task.NeuroImage · 2019Article
- Whole-ventricular irradiation for intracranial germ cell tumors: Dosimetric comparison of pencil beam scanned protons, intensity-modulated radiotherapy and volumetric-modulated arc therapy.Clinical and translational radiation oncology · 2019Article
- The relationship between radiotherapy dose and cognitive outcomes in functional brain network hubs of glioma patients with predominantly left frontal lobe lesions.Neuro-oncology advancesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eekers et al. have recently proposed a neuro-oncology atlas, which was co-authored by most centers associated in the European Proton Therapy Network (EPTN; Figure 1). With the introduction of new treatment techniques, such as integrated magnetic resonance imaging and linear accelerators (MR-linac) or particle therapy, the prediction of clinical efficacy of these more costly treatment modalities becomes more relevant. One of the side-effects of brain irradiation, being cognitive decline, is one of the toxicities most difficult to measure and predict. In order to validly compare different treatment modalities, 1) a uniform nomenclature of the organs at risk (OARs), 2) uniform atlas-based delineation [
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.