Evidence map›Paper›PMID 29594213›Full record

ArticleClinical and translational radiation oncology2017

Survival and failure types after radiation therapy of vulvar cancer.

Christina Steen Vorbeck, Ivan Richter Vogelius, Marie Louise Vorndran Cøln Banner-Voigt, Hanne From Mathiesen, Mansoor Raza Mirza

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Christina Steen VorbeckDepartment of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark.
Ivan Richter VogeliusDepartment of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark.
Marie Louise Vorndran Cøln Banner-VoigtDepartment of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark.
Hanne From MathiesenDepartment of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark.
Mansoor Raza MirzaDepartment of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark.
Rigshospitalet · DKCopenhagen University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeDescribe the survival rates and distribution of events on competing failure types in vulvar carcinoma after treatment with chemoradiation (CRT) or radiation (RT) alone. MATERIAL AND

methodsWe included patients with vulvar carcinoma treated with CRT or RT between 2009 and 2014. Survival was estimated using the Kaplan-Meier method. We performed a competing risk analysis and included five competing events: loco-regional failure (LRF), distant metastasis, LRF plus distant metastasis, and death without evidence of disease, with the remaining patients denoted alive without evidence of disease.

results87 patients were treated. Progression free survival (PFS) and overall survival (OS) at 3 years were 40% and 57%, respectively. 41.3% of patients relapsed, most often loco-regionally. We saw significantly worse PFS and OS for patients older than 68 (

conclusionsLRF was the most common event. PFS and OS were inferior for elderly patients and patients treated definitively. A better understanding of these differences may be used to define risk adapted treatment strategies.

Indexed as

ChemoradiationElderlyFailure typesRadiationVulvar cancer

Identifiers

PMID29594213
PMCPMC5833899
OpenAlexW2733256209

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.