Evidence map›Paper›PMID 29594131›Full record

ArticleMolecular neuropsychiatry2018

A Genome-Wide Search for Bipolar Disorder Risk Loci Modified by Mitochondrial Genome Variation.

Euijung Ryu, Malik Nassan, Gregory D Jenkins, Sebastian M Armasu, Ana Andreazza, Susan L McElroy, Marquis P Vawter, Mark A Frye, Joanna M Biernacka

Open access · bronzeAbstract read
In one paragraph

Article in Molecular neuropsychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  8. Association ofHereditas · 2019
    Article
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  10. Further Evidence of an Association betweenMolecular neuropsychiatry · 2018
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Euijung RyuDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Malik NassanDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.
Gregory D JenkinsDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Sebastian M ArmasuDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Ana AndreazzaDepartment of Department of Psychiatry and Pharmacology, University of Toronto, Toronto, ON, Canada.
Susan L McElroyDepartment of Lindner Center of HOPE, Mason, OH, USA.
Marquis P VawterDepartment of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine, Irvine, CA, USA.
Mark A FryeDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.
Joanna M BiernackaDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Florida · USLindner Center of HOPE · USMayo Clinic · USMayo Clinic in Arizona · USUniversity of California, Irvine · USUniversity of Toronto · CAWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial DNA mutations have been reported to be associated with bipolar disorder (BD). In this study, we performed genome-wide analyses to assess mitochondrial single-nucleotide polymorphism (mtSNP) effects on BD risk and early-onset BD (EOBD) among BD patients, focusing on interaction effects between nuclear SNPs (nSNPs) and mtSNPs. Common nSNP and mtSNP data from European American BD cases (

Indexed as

Bipolar disorderGenome-wide association studyInteractionMitochondrial genomeSingle-nucleotide polymorphism

Identifiers

PMID29594131
PMCPMC5836158
OpenAlexW2766440722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.