Evidence map›Paper›PMID 29594092›Full record

ArticleFrontiers in public health2018

Herpes Zoster in Persons Living with HIV-1 Infection: Viremia and Immunological Defects Are Strong Risk Factors in the Era of Combination Antiretroviral Therapy.

Nathaniel B Erdmann, Heather A Prentice, Anju Bansal, Howard W Wiener, Greer Burkholder, Sadeep Shrestha, Jianming Tang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05898464 (Immunogenicity and Safety of Recombinant Zoster Vaccine in People Living With HIV), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05898464 phase4completednot on this mapstarted 2023, after this paper: background citation

Immunogenicity and Safety of Recombinant Zoster Vaccine in People Living With HIV

TypeinterventionalSponsorSeoul National University HospitalRan2023 to 2026Enrolled71ConditionsVaccination, Infection, Vaccine Adverse ReactionArmsRecombinant zoster vaccination
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Herpes Zoster Rates Continue to Decline in People Living With Human Immunodeficiency Virus but Remain Higher Than Rates Reported in the General US Population.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nathaniel B ErdmannDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Heather A PrenticeDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Anju BansalDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Howard W WienerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Greer BurkholderDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Sadeep ShresthaDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Jianming TangDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
University of Alabama at Birmingham · US

Funding

Unsolicited R24 for the CFAR-Network of Integrated Clinical Sciences, CNICSR24AI067039 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael S. Saag · 2006 to 2026
$99.4M
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI OLAF KUTSCH · 1988 to 2026
$84.1M
Viral adaptation to CD4 T cell responses and the impact on HIV immunityK08AI129705 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ERDMANN, NATHANIEL BERNARD · 2017 to 2021
$930k
Multidisciplinary Evaluation of Accelerated Aging in HIV-1 InfectionR21AG051309 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TANG, JIANMING · 2017 to 2018
$408k
Immunologic Health in Aging PLWHR21AI134282 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TANG, JIANMING · 2018 to 2019
$408k
NIAID NIH HHS K08 AI129705NIAID NIH HHS P30 AI027767NIAID NIH HHS R21 AI134282NIAID NIH HHS R24 AI067039NIA NIH HHS R21 AG051309
6 · The paper itself

Abstract

In a cohort of 4,225 persons living with human immunodeficiency virus type 1 (HIV-1) infection (PLWH) enrolled at a southeastern US clinic, the overall rate of incident herpes zoster (HZ) was 101 per 10,000 person-years (PY) between January 1999 and 2017, which nearly quadruples the rate reported for the general US population. In the same cohort, the median age of HZ diagnosis was 39.5 years [interquartile range (IQR) 31.5-49.2] in African American (AA) and 39.1 years (IQR 34.9-45.2) in European American (EA) PLWH, with the highest incidence seen in PLWH who were over 50 years old (144 and 93 per 10,000 PY in AA and EA, respectively,

Indexed as

correlationepidemiologyherpes zosterhuman immunodeficiency virus type 1incident rate

Identifiers

PMID29594092
PMCPMC5857573
OpenAlexW2791142897

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.