Evidence map›Paper›PMID 29594067›Full record

ArticleFrontiers in cellular and infection microbiology2018

Route of Glucose Uptake in the Group a Streptococcus Impacts SLS-Mediated Hemolysis and Survival in Human Blood.

Ganesh S Sundar, Emrul Islam, Rezia D Braza, Aliyah B Silver, Yoann Le Breton, Kevin S McIver

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. PRD-Containing Virulence Regulators (PCVRs) in Pathogenic Bacteria.Frontiers in cellular and infection microbiology · 2021
    Review
  10. Article
  11. Pathogenicity Induced by Invasive Infection ofFrontiers in microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ganesh S SundarDepartment of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, University of Maryland, College Park, College Park, MD, United States.
Emrul IslamDepartment of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, University of Maryland, College Park, College Park, MD, United States.
Rezia D BrazaDepartment of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, University of Maryland, College Park, College Park, MD, United States.
Aliyah B SilverDepartment of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, University of Maryland, College Park, College Park, MD, United States.
Yoann Le BretonDepartment of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, University of Maryland, College Park, College Park, MD, United States.
Kevin S McIverDepartment of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, University of Maryland, College Park, College Park, MD, United States.
University of Maryland, College Park · US

Funding

PRD-Containing Virulence Regulators of Pathogenic StreptococciR01AI047928 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI MCIVER, KEVIN S. · 2001 to 2023
$6.5M
Training in Host-pathogens interactionsT32AI089621 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI LEE, VINCENT T, MCIVER, KEVIN S. · 2010 to 2025
$2.1M
NIAID NIH HHS R01 AI047928NIAID NIH HHS T32 AI089621
6 · The paper itself

Abstract

The transport and metabolism of glucose has been shown to have far reaching consequences in the transcriptional profile of many bacteria. As glucose is most often the preferred carbon source for bacteria, its presence in the environment leads to the repression of many alternate carbohydrate pathways, a condition known as carbon catabolite repression (CCR). Additionally, the expression of many virulence factors is also dependent on the presence of glucose. Despite its importance, little is known about the transport routes of glucose in the human pathogen

Indexed as

AnimalsBacterial ProteinsBlood GlucoseCarbohydrate MetabolismCatabolite RepressionDisease Models, AnimalFemaleGlucokinaseGlucoseHemolysisHumansMetabolic Networks and PathwaysMiceMutationPhosphotransferasesRepressor ProteinsBacterial ProteinsBlood GlucoseGlucokinaseGlucosePhosphotransferasesRepressor Proteinsstreptolysin SStreptolysinsglucose uptake and metabolismgroup A streptococcuspathophysiologyphosphotransferase systemStreptolysin S

Identifiers

PMID29594067
PMCPMC5861209
OpenAlexW2792235546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.