Evidence map›Paper›PMID 29593958›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2018

3D-Bioprinted Osteoblast-Laden Nanocomposite Hydrogel Constructs with Induced Microenvironments Promote Cell Viability, Differentiation, and Osteogenesis both In Vitro and In Vivo.

Xinyun Zhai, Changshun Ruan, Yufei Ma, Delin Cheng, Mingming Wu, Wenguang Liu, Xiaoli Zhao, Haobo Pan, William Weijia Lu

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
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  5. Article
  6. Review
  7. Article
  8. Heterogeneous and Composite Bioinks for 3D-Bioprinting of Complex Tissue.Biomedical materials & devices (New York, N.Y.) · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
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  15. Review
  16. Article
  17. 3D-Printed GelMA/PEGDA/F127DA Scaffolds for Bone Regeneration.Journal of functional biomaterials · 2023
    Article
  18. Review
  19. Review
  20. Up-to-date progress in bioprinting of bone tissue.International journal of bioprinting · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xinyun ZhaiResearch Center for Human Tissue and Organs Degeneration Institute Biomedical and Biotechnology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China.
Changshun RuanResearch Center for Human Tissue and Organs Degeneration Institute Biomedical and Biotechnology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China.ORCID 0000-0001-6320-7189
Yufei MaResearch Center for Human Tissue and Organs Degeneration Institute Biomedical and Biotechnology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China.
Delin ChengResearch Center for Human Tissue and Organs Degeneration Institute Biomedical and Biotechnology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China.
Mingming WuResearch Center for Human Tissue and Organs Degeneration Institute Biomedical and Biotechnology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China.
Wenguang LiuSchool of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional Materials Tianjin University Tianjin 300352 China.
Xiaoli ZhaoResearch Center for Human Tissue and Organs Degeneration Institute Biomedical and Biotechnology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China.
Haobo PanResearch Center for Human Tissue and Organs Degeneration Institute Biomedical and Biotechnology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China.
William Weijia LuDepartment of Orthopaedic and Traumatology The University of Hong Kong 21 Sassoon Road Pokfulam Hong Kong 999077 China.

Funding

The PERMSS Project-Promoting Education and Research on Mood, Stress, & SubstancesK23AA020316 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI ALVANZO, ANIKA A.H. · 2012 to 2016
$910k
NIAAA NIH HHS K23 AA020316
6 · The paper itself

Abstract

An osteoblast-laden nanocomposite hydrogel construct, based on polyethylene glycol diacrylate (PEGDA)/laponite XLG nanoclay ([Mg

Indexed as

3D‐bioprintingnanocomposite hydrogelsosteoblast‐laden constructsosteogenesis capability

Identifiers

PMID29593958
PMCPMC5867050

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.