Evidence map›Paper›PMID 29593934›Full record

ArticleJournal of biometrics & biostatistics2015

Semiparametric Mixed Models for Medical Monitoring Data: An Overview.

R D Szczesniak, D Li, S A Raouf

Abstract read
In one paragraph

Article in Journal of biometrics & biostatistics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

R D SzczesniakDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.
D LiDepartment of Mathematical Sciences, University of Cincinnati, Cincinnati, USA.
S A RaoufDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.

Funding

VITAMIN K DEFICIENCY IN CHOLESTATIC LIVER DISEASEM01RR008084 · NCRR · CINCINNATI CHILDRENS HOSP MED CTR · PI HEUBI, JAMES E. · 1994 to 2009
$20.6M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR026314 · NCRR · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2009 to 2011
$14.3M
Vascular Functions in Children with Sleep Disordered BreathingR01HL080670 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI AMIN, RAOUF S. · 2006 to 2010
$2.8M
Preventing rapid decline in CF: statistical research career commitmentK25HL125954 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI SZCZESNIAK, RHONDA · 2015 to 2019
$762k
NCRR NIH HHS M01 RR008084NCRR NIH HHS UL1 RR026314NHLBI NIH HHS K25 HL125954NHLBI NIH HHS R01 HL080670
6 · The paper itself

Abstract

The potential to characterize nonlinear progression over time is now possible in many health conditions due to advancements in medical monitoring and more frequent data collection. It is often of interest to investigate differences between experimental groups in a study or identify the onset of rapid changes in the response of interest using medical monitoring data; however, analytic challenges emerge. We review semiparametric mixed-modeling extensions that accommodate medical monitoring data. Throughout the review, we illustrate these extensions to the semiparametric mixed-model framework with an application to prospective clinical data obtained from 24-hour ambulatory blood pressure monitoring, where it is of interest to compare blood pressure patterns from children with obstructive sleep apnea to those arising from healthy controls.

Indexed as

Ambulatory blood pressureCovariance modelsFunctional data analysisLinear mixed modelsLongitudinal dataNonparametric regressionObstructive sleep apneaPenalized splinesSemiparametric regressionSerial correlation

Identifiers

PMID29593934
PMCPMC5868984

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.