Evidence map›Paper›PMID 29593914›Full record

ArticleCase reports in critical care2018

Rituximab Induced Pulmonary Edema Managed with Extracorporeal Life Support.

Jacob R Miller, Warren Isakow, Muhammad F Masood, Patrick Aguilar, Kristen M Sanfilippo, Keki R Balsara, Akinobu Itoh

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in critical care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jacob R MillerDivision of Cardiothoracic Surgery, Washington University, St. Louis, MO, USA.ORCID 0000-0002-3380-3948
Warren IsakowDivision of Pulmonary Critical Care, Washington University, St. Louis, MO, USA.
Muhammad F MasoodDivision of Cardiothoracic Surgery, Washington University, St. Louis, MO, USA.
Patrick AguilarDivision of Pulmonary Critical Care, Washington University, St. Louis, MO, USA.
Kristen M SanfilippoDivision of Hematology, Washington University, St. Louis, MO, USA.
Keki R BalsaraDivision of Cardiothoracic Surgery, Washington University, St. Louis, MO, USA.
Akinobu ItohDivision of Cardiothoracic Surgery, Washington University, St. Louis, MO, USA.ORCID 0000-0002-3049-3411

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Though rare, rituximab has been reported to induce severe pulmonary edema. We describe the first report of ECLS utilization for this indication. A 31-year-old female with severe thrombotic thrombocytopenic purpura developed florid pulmonary edema after rituximab infusion. Despite advanced ventilatory settings, she developed severe respiratory acidosis and remained hypoxemic with a significant vasopressor requirement. Since her pulmonary insult was likely transient, ECLS was considered. Due to combined cardiorespiratory failure, she received support with peripheral venoarterial ECLS. During her ECLS course, she received daily plasmapheresis and high dose steroids. Her pulmonary function recovered and she was decannulated after 8 days. She was discharged after 23 days without residual sequelae.

Identifiers

PMID29593914
PMCPMC5822923

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.