Evidence map›Paper›PMID 29593818›Full record

ArticleArchives of medical science : AMS2018

Natural approaches in metabolic syndrome management.

Angelo Maria Patti, Khalid Al-Rasadi, Rosaria Vincenza Giglio, Dragana Nikolic, Carlo Mannina, Giuseppa Castellino, Roberta Chianetta, Maciej Banach, Arrigo F G Cicero, Giuseppe Lippi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 3 pooled it
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 3 syntheses or guidelines pooled it, 138 citations in OpenAlex.

  1. Effect ofCurrent medicinal chemistry · 2025
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  9. Multiple functions of policosanol in elderly patients with dyslipidemia.The Journal of international medical research · 2020
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  11. AltilixNutrients · 2019
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  18. Investigation ofFrontiers in pharmacology · 2025
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 4 countries.

Angelo Maria PattiBiomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Italy.
Khalid Al-RasadiDepartment of Clinical Biochemistry, Sultan Qaboos University, Muscat, Oman.
Rosaria Vincenza GiglioBiomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Italy.
Dragana NikolicBiomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Italy.
Carlo ManninaBiomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Italy.
Giuseppa CastellinoBiomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Italy.
Roberta ChianettaBiomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Italy.
Maciej BanachDepartment of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Lodz, Poland.
Arrigo F G CiceroDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Giuseppe LippiSection of Clinical Biochemistry, University of Verona, Verona, Italy.
Giuseppe MontaltoBiomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Italy.
Manfredi RizzoBiomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Italy.
Peter P TothCGH Medical Center, Sterling, Illinois; Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Istituto Euro Mediterraneo di Scienza e Tecnologia · ITUniversity of Palermo · ITJohns Hopkins University · USMedical University of Lodz · PLSultan Qaboos University · OMUniversity of Bologna · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic syndrome (MetS) is characterized as a group of cardiometabolic risk factors that raise the risk for heart disease and other health problems, such as diabetes mellitus and stroke. Treatment strategies include pharmacologic interventions and supplementary (or "alternative") treatments. Nutraceuticals are derived from food sources (isolated nutrients, dietary supplements and herbal products) that are purported to provide health benefits, in addition to providing basic nutritional value. Nutraceuticals are claimed to prevent chronic diseases, improve health, delay the aging process, increase life expectancy, and support the structure and function of the body. The study of the beneficial effects of nutraceuticals in patients with MetS, including product standardization, duration of supplementation and definition of optimal dosing, could help better define appropriate treatment. This review focuses on widely marketed nutraceuticals (namely polyphenols, omega-3 fatty acids, macroelements and vitamins) with clinically demonstrated effects on more than one component of MetS.

Indexed as

cardiovascular riskmacroelementsmetabolic syndromenutraceuticalsomega-3 fatty acidspolyphenolsvitamins

Identifiers

PMID29593818
PMCPMC5868676
OpenAlexW2737757244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.