ReviewNeural plasticity2018
Precision Light for the Treatment of Psychiatric Disorders.
Review in Neural plasticity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Systematic review of drugs that modify the circadian system's phase-shifting responses to light exposure.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Pooled it
- Blue light treatment of psychiatric disorders: relationships with systemic inflammation, lipid metabolism, and clinical symptoms.BMC psychiatry · 2025Article
- Why humans evolved blue eyes.Frontiers in psychology · 2025Article
- Sleep Deprivation Does Not Influence Photic Resetting of Circadian Activity Rhythms in Drosophila.Clocks & sleep · 2022Article
- Age-related and individual features of the HPA axis stress responsiveness under constant light in nonhuman primates.Frontiers in endocrinology · 2022Article
- The Importance of Early Identification for Parkinson's Disease Patients with Postural Instability and Gait Disturbance.Computational intelligence and neuroscience · 2022Article
- "Shedding Light on Light": A Review on the Effects on Mental Health of Exposure to Optical Radiation.International journal of environmental research and public health · 2021Review
- Sleep and Memory Consolidation Dysfunction in Psychiatric Disorders: Evidence for the Involvement of Extracellular Matrix Molecules.Frontiers in neuroscience · 2021Review
- Circadian Responses to Light-Flash Exposure: Conceptualization and New Data Guiding Future Directions.Frontiers in neurology · 2021Article
- Epilepsy and Its Interaction With Sleep and Circadian Rhythm.Frontiers in neurology · 2020Review
- Circadian Responses to Fragmented Light: Research Synopsis in Humans.The Yale journal of biology and medicine · 2019Review
- Chronobiology of limbic seizures: Potential mechanisms and prospects of chronotherapy for mesial temporal lobe epilepsy.Neuroscience and biobehavioral reviews · 2019Review
- Responses to Intermittent Light Stimulation Late in the Night Phase Before Dawn.Clocks & sleep · 2019Article
- Circadian phase-shifting by light: Beyond photons.Neurobiology of sleep and circadian rhythms · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circadian timekeeping can be reset by brief flashes of light using stimulation protocols thousands of times shorter than those previously assumed to be necessary for traditional phototherapy. These observations point to a future where flexible architectures of nanosecond-, microsecond-, and millisecond-scale light pulses are compiled to reprogram the brain's internal clock when it has been altered by psychiatric illness or advanced age. In the current review, we present a chronology of seminal experiments that established the synchronizing influence of light on the human circadian system and the efficacy of prolonged bright-light exposure for reducing symptoms associated with seasonal affective disorder. We conclude with a discussion of the different ways that precision flashes could be parlayed during sleep to effect neuroadaptive changes in brain function. This article is a contribution to a special issue on
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.