Evidence map›Paper›PMID 29593550›Full record

ArticleFrontiers in physiology2018

Naltrexone Reverses Ethanol Preference and Protein Kinase C Activation in

Rajeswari Koyyada, Nilesh Latchooman, Julius Jonaitis, Samir S Ayoub, Olivia Corcoran, Stefano O Casalotti

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Flying Together:International journal of molecular sciences · 2020
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rajeswari KoyyadaMedicines Research Group, School of Health, Sport and Bioscience, University of East London, London, United Kingdom.
Nilesh LatchoomanMedicines Research Group, School of Health, Sport and Bioscience, University of East London, London, United Kingdom.
Julius JonaitisMedicines Research Group, School of Health, Sport and Bioscience, University of East London, London, United Kingdom.
Samir S AyoubMedicines Research Group, School of Health, Sport and Bioscience, University of East London, London, United Kingdom.
Olivia CorcoranMedicines Research Group, School of Health, Sport and Bioscience, University of East London, London, United Kingdom.
Stefano O CasalottiMedicines Research Group, School of Health, Sport and Bioscience, University of East London, London, United Kingdom.
University of East London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol use disorder (AUD) is a major health, social and economic problem for which there are few effective treatments. The opiate antagonist naltrexone is currently prescribed clinically with mixed success. We have used naltrexone in an established behavioral assay (CAFE) in

Indexed as

CAFE assayDrosophila melanogasterethanolnaltrexoneopiate antagonistPKC

Identifiers

PMID29593550
PMCPMC5861182
OpenAlexW2791413157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.