Evidence map›Paper›PMID 29593548›Full record

ArticleFrontiers in physiology2018

Impact of Nitric Oxide Bioavailability on the Progressive Cerebral and Peripheral Circulatory Impairments During Aging and Alzheimer's Disease.

Massimo Venturelli, Anna Pedrinolla, Ilaria Boscolo Galazzo, Cristina Fonte, Nicola Smania, Stefano Tamburin, Ettore Muti, Lucia Crispoltoni, Annamaria Stabile, Alessandra Pistilli and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 59 citations in OpenAlex.

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  6. Can Beetroot (Nutrients · 2025
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  19. The Brain and Spinal Microvasculature in Normal Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Massimo VenturelliDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Anna PedrinollaDepartment of Medicine, University of Verona, Verona, Italy.
Ilaria Boscolo GalazzoDepartment of Computer Science, University of Verona, Verona, Italy.
Cristina FonteDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Nicola SmaniaDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Stefano TamburinDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Ettore MutiMons. Mazzali Foundation, Mantua, Italy.
Lucia CrispoltoniDepartment of Surgical and Biomedical Sciences, Section of Human Anatomy, School of Medicine, University of Perugia, Perugia, Italy.
Annamaria StabileDepartment of Surgical and Biomedical Sciences, Section of Human Anatomy, School of Medicine, University of Perugia, Perugia, Italy.
Alessandra PistilliDepartment of Surgical and Biomedical Sciences, Section of Human Anatomy, School of Medicine, University of Perugia, Perugia, Italy.
Mario RendeDepartment of Surgical and Biomedical Sciences, Section of Human Anatomy, School of Medicine, University of Perugia, Perugia, Italy.
Francesca B PizziniNeuroradiology, Department of Diagnostics and Pathology, Verona University Hospital, Verona, Italy.
Federico SchenaDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
University of Verona · ITUniversity of Perugia · ITFondazione Mons Arrigo Mazzali · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advanced aging, vascular dysfunction, and nitric oxide (NO) bioavailability are recognized risk factors for Alzheimer's disease (AD). However, the contribution of AD,

Indexed as

agingAlzheimer's diseasecirculationnitric oxidevascular dysfunction

Identifiers

PMID29593548
PMCPMC5861210
OpenAlexW2793587028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.