Evidence map›Paper›PMID 29593545›Full record

ArticleFrontiers in pharmacology2018

The Cytochrome P450-Mediated Metabolism Alternation of Four Effective Lignans From

Rongrong Wu, Zhiyong Xiao, Xiaorui Zhang, Feng Liu, Wenxia Zhou, Yongxiang Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Nanotheranostics · 2026
    Article
  2. Article
  3. Molecules (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rongrong WuState Key Laboratory of Toxicology and Medical Countermeasures, Department of Neuroimmunopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Zhiyong XiaoState Key Laboratory of Toxicology and Medical Countermeasures, Department of Neuroimmunopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Xiaorui ZhangState Key Laboratory of Toxicology and Medical Countermeasures, Department of Neuroimmunopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Feng LiuState Key Laboratory of Toxicology and Medical Countermeasures, Department of Neuroimmunopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Wenxia ZhouState Key Laboratory of Toxicology and Medical Countermeasures, Department of Neuroimmunopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Yongxiang ZhangState Key Laboratory of Toxicology and Medical Countermeasures, Department of Neuroimmunopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
302 Military Hospital of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is highly valuable to study the pharmacokinetics of herbal components under the pathological condition of liver dysfunction for safe and rational use of herbal medicines. In this study, the pharmacokinetic profiles of four effective lignans from

Indexed as

cytochrome P450(CYP450)lignansliver injurypharmacokineticsSchisandra chinensis (SC)

Identifiers

PMID29593545
PMCPMC5861220
OpenAlexW2793209877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.