ArticleFrontiers in pharmacology2018
East Indian Sandalwood Oil Is a Phosphodiesterase Inhibitor: A New Therapeutic Option in the Treatment of Inflammatory Skin Disease.
Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 23 citations in OpenAlex.
- Promising Antimicrobial Activities of Essential Oils and Probiotic Strains on Chronic Wound Bacteria.Biomedicines · 2025Article
- Effects of extended dietary supplementation with Santalum album essential oil on hemato-biochemical changes, innate immune response, antioxidant status, and expression of related gene in Nile tilapia (Oreochromis niloticus).Fish physiology and biochemistry · 2024Article
- The Assessment of Quality of Products Called Sandalwood Oil Based on the Information Provided by Manufacturer of the Oil on Polish, German, and English Websites.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Fractionated Antioxidant and Anti-inflammatory Kernel Oil fromMolecules (Basel, Switzerland) · 2019Article
- East Indian sandalwood (RSC advances · 2018Article
- Sandalwood Album Oil as a Botanical Therapeutic in Dermatology.The Journal of clinical and aesthetic dermatology · 2017Review
- Re-discovering Sandalwood: Beyond Beauty and Fragrance.Indian dermatology online journalArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyclic adenosine monophosphate phosphodiesterases (PDEs) regulate pro-inflammatory cytokine production. One isoform, PDE4, is overactive in chronic relapsing inflammatory skin diseases: psoriasis and eczema/atopic dermatitis, and in several cancers. East Indian sandalwood oil (EISO) has significant anti-inflammatory properties. Here, we report that 75% of pediatric eczema/atopic dermatitis patients treated with topical EISO formulations achieved a >50% reduction in their Eczema Area and Severity Index score. EISO treatment of a psoriasis model reduced PDE4 expression and reversed histopathology. EISO directly inhibited PDE enzymatic activity
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Registered trials
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