Evidence map›Paper›PMID 29593504›Full record

ReviewFrontiers in neural circuits2018

Neuromodulatory Correlates of Pupil Dilation.

Rylan S Larsen, Jack Waters

Abstract readReview
In one paragraph

Review in Frontiers in neural circuits, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Modality-general sensitivity of pupil responses to regularity violations.Cognitive, affective & behavioral neuroscience · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Most Ventral Pallidal Cholinergic Neurons Are Bursting Basal Forebrain Cholinergic Neurons with Mesocorticolimbic Connectivity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  11. Article
  12. Article
  13. Dissociable Pupil and Oculomotor Markers of Attention Allocation and Distractor Suppression during Listening.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rylan S LarsenAllen Institute for Brain Science, Seattle, WA, United States.
Jack WatersAllen Institute for Brain Science, Seattle, WA, United States.

Funding

Direct nicotinic excitation of layer 5 neocortical pyramidal neuronsR01NS078067 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WATERS, JACK · 2012 to 2016
$1.9M
NINDS NIH HHS R01 NS078067
6 · The paper itself

Abstract

Pupillometry has long been used as a measure of brain state. Changes in pupil diameter are thought to coincide with the activity of neuromodulators, including noradrenaline and acetylcholine, producing alterations in the brain state and corresponding changes in behavior. Here we review mechanisms underlying the control of pupil diameter and how these mechanisms are correlated with changes in cortical activity and the recruitment of neuromodulatory circuits.

Indexed as

AnimalsHumansNeocortexNeuronsOrgan SizePupilacetylcholineneuromodulationnoradrenalinenorepinephrinepupillometry

Identifiers

PMID29593504
PMCPMC5854659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.