Evidence map›Paper›PMID 29593408›Full record

ArticleInternational journal of nanomedicine2018

Synthesis and characterization of multifunctional gold nanoclusters for application in radiation therapy.

Richa Baronia, Manjri Singh, Rajat B Gupta, Stalin Karuppiah, Rajiv Kumar, Jodi Belz, Rishi Shanker, Srinivas Sridhar, Surinder P Singh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Richa BaroniaCSIR-National Physical Laboratory, Dr KS Krishnan Marg, New Delhi, India.
Manjri SinghCSIR-National Physical Laboratory, Dr KS Krishnan Marg, New Delhi, India.
Rajat B GuptaCSIR-National Physical Laboratory, Dr KS Krishnan Marg, New Delhi, India.
Stalin KaruppiahCSIR-National Physical Laboratory, Dr KS Krishnan Marg, New Delhi, India.
Rajiv KumarNanomedicine Science and Technology Center, Northeastern University, Boston, MA, USA.
Jodi BelzNanomedicine Science and Technology Center, Northeastern University, Boston, MA, USA.
Rishi ShankerInstitute of Life Sciences, Ahmedabad University, Ahmedabad, India.
Srinivas SridharNanomedicine Science and Technology Center, Northeastern University, Boston, MA, USA.
Surinder P SinghCSIR-National Physical Laboratory, Dr KS Krishnan Marg, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold nanoparticles, because of their high radiation absorption coefficient and efficient generation of secondary photoelectrons, have been predicted to enhance therapeutic efficacy in radiation therapy. However, high dose for effective treatment limits their use. We have synthesized multifunctional gold nanoclusters (GNCs) that can be used for imaging and radiation therapy. The designed GNCs have been characterized for their physicochemical properties, biocompatibility, and their radiation dose enhancement potential on PC3 cell lines.

Indexed as

Absorption, RadiationCell Line, TumorCell SurvivalDrug Screening Assays, AntitumorGoldHumansMetal NanoparticlesNeoplasmsRadiation-Sensitizing AgentsSpectroscopy, Fourier Transform InfraredGoldRadiation-Sensitizing Agentsgold nanoclustersradiation therapy

Identifiers

PMID29593408
PMCPMC5863625

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.