Evidence map›Paper›PMID 29593332›Full record

ArticleInternational journal of oral science2017

The importance of a potential phosphorylation site in enamelin on enamel formation.

Wen-Juan Yan, Pan Ma, Ye Tian, Jing-Ya Wang, Chun-Lin Qin, Jian Q Feng, Xiao-Fang Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of oral science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. JBMR plus · 2026
    Article
  5. Functions of secretory calcium-binding phosphoproteins in dental mineralization.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Review
  6. Article
  7. The phosphorylation of serineMatrix biology : journal of the International Society for Matrix Biology · 2022
    Article
  8. Advanced materials for enamel remineralization.Frontiers in bioengineering and biotechnology · 2022
    Review
  9. Review
  10. Article
  11. Article
  12. Protein nanoribbons template enamel mineralization.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. MutantPeerJ · 2020
    Article
  14. ENAM mutations and digenic inheritance.Molecular genetics & genomic medicine · 2019
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Wen-Juan YanDepartment of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, USA.
Pan MaDepartment of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, USA.
Ye TianDepartment of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, USA.
Jing-Ya WangDepartment of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, USA.
Chun-Lin QinDepartment of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, USA.
Jian Q FengDepartment of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, USA.
Xiao-Fang WangDepartment of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, USA.
Texas A&M University · US

Funding

The Role of FAM20B-catalyzed Proteoglycans in Tooth DevelopmentR01DE026461 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI WANG, XIAOFANG · 2017 to 2021
$1.8M
NIDCR NIH HHS R01 DE026461
6 · The paper itself

Abstract

Enamelin (ENAM) has three putative phosphoserines (pSers) phosphorylated by a Golgi-associated secretory pathway kinase (FAM20C) based on their distinctive Ser-x-Glu (S-x-E) motifs. Fam20C-knockout mice show severe enamel defects similar to those in the Enam-knockout mice, implying an important role of the pSers in ENAM. To determine the role of pSer

Indexed as

AmeloblastsAmelogenesisAmelogeninAnimalsBlotting, WesternDental EnamelDental Enamel ProteinsImmunohistochemistryMiceMice, KnockoutMicroscopy, Electron, ScanningPhosphorylationSerineAmbn protein, mouseAmelogeninDental Enamel ProteinsSerinetuftelin

Identifiers

PMID29593332
PMCPMC5775333
OpenAlexW2783927640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.