Evidence map›Paper›PMID 29593097›Full record

ArticleThe Journal of biological chemistry2018

Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases.

Benoit Jacques, Mathieu Coinçon, Jurgen Sygusch

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Whole-Genome Resequencing ofInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. The metal cofactor: stationary or mobile?Applied microbiology and biotechnology · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Substrate Induced Movement of the Metal Cofactor between Active and Resting State.Angewandte Chemie (International ed. in English) · 2022
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Benoit JacquesFrom the Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Québec H3C 3J7, Canada.
Mathieu CoinçonFrom the Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Québec H3C 3J7, Canada.
Jurgen SyguschFrom the Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Québec H3C 3J7, Canada Jurgen.Sygusch@umontreal.ca.
Université de Montréal · CA

Funding

X-RAY STRUCTURE OF RIFM PROTEIN FROM THE BIOSYNTHESIS PATHWAY OF THE ANSAMYCIN AP41RR012408 · NCRR · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI ORVILLE, ALLEN M · 1998 to 2011
$32.2M
Macromolecular Crystallography at the National Synchrotron Light SourceP41GM103473 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI SWEET, ROBERT M · 2012 to 2013
$4.9M
CIHRNCRR NIH HHS P41 RR012408NIGMS NIH HHS P41 GM103473
6 · The paper itself

Abstract

Crystal structures of two bacterial metal (Zn

Indexed as

Catalytic DomainBinding SitesCatalysisCrystallography, X-RayFructoseFructose-Bisphosphate AldolaseHelicobacter pyloriHydrogen BondingModels, MolecularMutationProtein ConformationStereoisomerismSubstrate SpecificityZincFructoseFructose-Bisphosphate AldolaseZincactive site remodelingconformational changecrystal structureenzyme mechanismfructose-1,6-bisphosphate aldolaseHelicobacter pylorimetalloenzymezinc

Identifiers

PMID29593097
PMCPMC5961046
OpenAlexW2794543459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.