ArticleBMJ open2018
GCAT|Genomes for life: a prospective cohort study of the genomes of Catalonia.
Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Multiomic integration analysis identifies atherogenic metabolites mediating between novel immune genes and cardiovascular risk.Genome medicine · 2024Pooled it
- Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.Journal of medical genetics · 2018Pooled it
- BRCA1 c.68_69del as a founder variant in the Spanish Roma: prevalence and screening implications.European journal of human genetics : EJHG · 2026Article
- SARS-CoV-2 seroprevalence in Barcelona and Catalonia (Spain) after the 2020 lockdown.Scientific reports · 2026Article
- PolyGenie: a reproducible Nextflow pipeline for phenome-wide association studies using polygenic risk scores.NAR genomics and bioinformatics · 2026Article
- Pre-pandemic disease trajectories and genetic insights into long COVID susceptibility.BMC medicine · 2025Article
- Article
- Predicting recovery after stressors using step count data derived from activity monitors.NPJ digital medicine · 2025Article
- Bottlenecks in advancing and applying multiomic data integration-common data resources as rate-limiting drivers-the high-impact use case of atherosclerotic cardiovascular disease.Briefings in bioinformatics · 2025Review
- External exposome and incident asthma across the life course in 14 European cohorts: a prospective analysis within the EXPANSE project.The Lancet regional health. Europe · 2025Article
- Weighting health-related estimates in the GCAT cohort and the general population of Catalonia.Scientific reports · 2025Article
- Cohort profile: the CORDELIA study (Collaborative cOhorts Reassembled Data to study mEchanisms and Longterm Incidence of chronic diseAses).European journal of epidemiology · 2025Article
- Inferring past demography and genetic adaptation in Spain using the GCAT cohort.Scientific reports · 2025Article
- Outdoor artificial light-at-night and cardiometabolic disease risk: an urban perspective from the Catalan GCAT cohort study.American journal of epidemiology · 2025Article
- Risk, determinants, and persistence of long-COVID in a population-based cohort study in Catalonia.BMC medicine · 2025Article
- Stability of oral and fecal microbiome at room temperature: impact on diversity.Frontiers in microbiomes · 2025Article
- Article
- Sex-Stratified Genome-Wide Association Study in the Spanish Population Identifies a Novel Locus for Lacunar Stroke.Stroke · 2024Article
- Sex-specific chrono-nutritional patterns and association with body weight in a general population in Spain (GCAT study).The international journal of behavioral nutrition and physical activity · 2024Article
- Decoding depression by exploring the exposome-genome edge amidst COVID-19 lockdown.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe prevalence of chronic non-communicable diseases (NCDs) is increasing worldwide. NCDs are the leading cause of both morbidity and mortality, and it is estimated that by 2030, they will be responsible for 80% of deaths across the world. The Genomes for Life (GCAT) project is a long-term prospective cohort study that was designed to integrate and assess the role of epidemiological, genomic and epigenomic factors in the development of major chronic diseases in Catalonia, a north-east region of Spain.
participantsAt the end of 2017, the GCAT Study will have recruited 20 000 participants aged 40-65 years. Participants who agreed to take part in the study completed a self-administered computer-driven questionnaire, and underwent blood pressure, cardiac frequency and anthropometry measurements. For each participant, blood plasma, blood serum and white blood cells are collected at baseline. The GCAT Study has access to the electronic health records of the Catalan Public Healthcare System. Participants will be followed biannually at least 20 years after recruitment. FINDINGS TO DATE: Among all GCAT participants, 59.2% are women and 83.3% of the cohort identified themselves as Caucasian/white. More than half of the participants have higher education levels, 72.2% are current workers and 42.1% are classified as overweight (body mass index ≥25 and <30 kg/m FUTURE PLANS: The first follow-up study started in December 2017 and will end by March 2018. Residences of all subjects will be geocoded during the following year. Several genomic analyses are ongoing, and metabolomic and genomic integrations will be performed to identify underlying genetic variants, as well as environmental factors that influence metabolites.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.