Evidence map›Paper›PMID 29592970›Full record

ArticleJournal of cell science2018

Spatio-temporal MAPK dynamics mediate cell behavior coordination during fungal somatic cell fusion.

Antonio Serrano, Julia Illgen, Ulrike Brandt, Nils Thieme, Anja Letz, Alexander Lichius, Nick D Read, André Fleißner

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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  7. A dialogue-like cell communication mechanism is conserved in filamentous ascomycete fungi and mediates interspecies interactions.Proceedings of the National Academy of Sciences of the United States of America · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Antonio SerranoInstitut für Genetik, Technische Universität Braunschweig, Spielmannstraße 7, 38106 Braunschweig, Germany.
Julia IllgenInstitut für Genetik, Technische Universität Braunschweig, Spielmannstraße 7, 38106 Braunschweig, Germany.
Ulrike BrandtInstitut für Genetik, Technische Universität Braunschweig, Spielmannstraße 7, 38106 Braunschweig, Germany.
Nils ThiemeInstitut für Genetik, Technische Universität Braunschweig, Spielmannstraße 7, 38106 Braunschweig, Germany.
Anja LetzInstitut für Genetik, Technische Universität Braunschweig, Spielmannstraße 7, 38106 Braunschweig, Germany.ORCID 0000-0002-2323-7583
Alexander LichiusInstitute of Microbiology, University of Innsbruck, 6020 Innsbruck, Austria.
Nick D ReadManchester Fungal Infection Group, Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester M13 9NT, UK.
André FleißnerInstitut für Genetik, Technische Universität Braunschweig, Spielmannstraße 7, 38106 Braunschweig, Germany a.fleissner@tu-bs.de.ORCID 0000-0001-5841-3199
Technische Universität Braunschweig · DEUniversität Innsbruck · ATUniversity of Manchester · GB

Funding

Tools for Functional Analysis and Cell BiologyP01GM068087 · NIGMS · DARTMOUTH COLLEGE · PI DUNLAP, JAY C. · 2004 to 2013
$19.3M
Biotechnology and Biological Sciences Research Council BB/E010741/1NIGMS NIH HHS P01 GM068087
6 · The paper itself

Abstract

Mitogen-activated protein kinases (MAPKs) are conserved regulators of proliferation, differentiation and adaptation in eukaryotic cells. Their activity often involves changes in their subcellular localization, indicating an important role for these spatio-temporal dynamics in signal transmission. A striking model illustrating these dynamics is somatic cell fusion in

Indexed as

MAP Kinase Signaling SystemCell CommunicationCell FusionFungal ProteinsMitogen-Activated Protein KinasesNeurospora crassaSignal TransductionFungal ProteinsMitogen-Activated Protein KinasesCell communicationCell fusionDirected growthMAPK

Identifiers

PMID29592970
PMCPMC5992588
OpenAlexW2794717273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.