Evidence map›Paper›PMID 29592954›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Synergistic activity of cosecreted natural products from amoebae-associated bacteria.

Johannes Arp, Sebastian Götze, Ruchira Mukherji, Derek J Mattern, María García-Altares, Martin Klapper, Debra A Brock, Axel A Brakhage, Joan E Strassmann, David C Queller and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. The atypical organization of theJournal of bacteriology · 2024
    Review
  7. Does regulation hold the key to optimizing lipopeptide production inFrontiers in bioengineering and biotechnology · 2024
    Review
  8. Article
  9. Occurrence of D-amino acids in natural products.Natural products and bioprospecting · 2023
    Review
  10. Nonribosomal peptides protectChemical science · 2023
    Article
  11. Article
  12. Article
  13. Yellow polyketide pigment suppresses premature hatching in social amoeba.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Review
  15. Total Synthesis and Structure Correction of the Cyclic Lipodepsipeptide Orfamide A.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  16. Article
  17. Article
  18. Versatile role ofFrontiers in plant science · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Johannes ArpChemistry of Microbial Communication, Independent Junior Research Group, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), 07745 Jena, Germany.
Sebastian GötzeChemistry of Microbial Communication, Independent Junior Research Group, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), 07745 Jena, Germany.ORCID 0000-0002-4087-0225
Ruchira MukherjiChemistry of Microbial Communication, Independent Junior Research Group, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), 07745 Jena, Germany.
Derek J MatternDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology, HKI, 07745 Jena, Germany.
María García-AltaresDepartment of Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, HKI, 07745 Jena, Germany.
Martin KlapperChemistry of Microbial Communication, Independent Junior Research Group, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), 07745 Jena, Germany.
Debra A BrockDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.
Axel A BrakhageDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology, HKI, 07745 Jena, Germany.
Joan E StrassmannDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.ORCID 0000-0003-0638-8440
David C QuellerDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63130.
Bettina BardlDepartment of Bio Pilot Plant, Leibniz Institute for Natural Product Research and Infection Biology, HKI, 07745 Jena, Germany.
Karsten WillingDepartment of Bio Pilot Plant, Leibniz Institute for Natural Product Research and Infection Biology, HKI, 07745 Jena, Germany.
Gundela PeschelDepartment of Bio Pilot Plant, Leibniz Institute for Natural Product Research and Infection Biology, HKI, 07745 Jena, Germany.
Pierre StallforthChemistry of Microbial Communication, Independent Junior Research Group, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), 07745 Jena, Germany; pierre.stallforth@leibniz-hki.de.ORCID 0000-0001-7260-9921
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Investigating microbial interactions from an ecological perspective is a particularly fruitful approach to unveil both new chemistry and bioactivity. Microbial predator-prey interactions in particular rely on natural products as signal or defense molecules. In this context, we identified a grazing-resistant

Indexed as

Drug Synergism4-ButyrolactoneAnti-Bacterial AgentsBacterial ProteinsBiological ProductsDictyosteliumGenome, BacterialMethicillin-Resistant Staphylococcus aureusMupirocinPseudomonasQuorum SensingStaphylococcal Infections4-ButyrolactoneAnti-Bacterial AgentsBacterial ProteinsBiological Productshomoserine lactoneMupirocinN-hexanoyl-L-homoserine lactonenonribosomal peptidesPseudomonassocial amoebaestructure elucidationsynergy

Identifiers

PMID29592954
PMCPMC5899472
OpenAlexW2794839960

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.