Evidence map›Paper›PMID 29592890›Full record

ArticleDisease models & mechanisms2018

A novel zebrafish intestinal tumor model reveals a role for

Sora Enya, Koichi Kawakami, Yutaka Suzuki, Shinpei Kawaoka

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Consequences of Cancer on ZebrafishEcology and evolution · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Dietary Inclusion of Seabuckthorn (Frontiers in physiology · 2022
    Article
  12. Review
  13. Article
  14. Article
  15. Tipping the Scales With Zebrafish to Understand Adaptive Tumor Immunity.Frontiers in cell and developmental biology · 2021
    Review
  16. Review
  17. Article
  18. Zebrafish as a Model to Study Cholestatic Liver Diseases.Methods in molecular biology (Clifton, N.J.) · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sora EnyaAdvanced Telecommunications Research Institute International (ATR), The Thomas N. Sato BioMEC-X Laboratories, Kyoto 619-0288, Japan.
Koichi KawakamiDivision of Molecular and Developmental Biology, National Institute of Genetics, and Department of Genetics, SOKENDAI (The Graduate University for Advanced Studies), Mishima, Shizuoka 411-8540, Japan.ORCID 0000-0001-9993-1435
Yutaka SuzukiThe University of Tokyo, Graduate School of Frontier Science, Kashiwa 277-8651, Japan.
Shinpei KawaokaAdvanced Telecommunications Research Institute International (ATR), The Thomas N. Sato BioMEC-X Laboratories, Kyoto 619-0288, Japan kawaokashinpei@gmail.com.ORCID 0000-0003-4064-6781
Japan Science and Technology Agency · JPNational Institute of Genetics · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nature of host organs and genes that underlie tumor-induced physiological disruption on the host remains ill-defined. Here, we establish a novel zebrafish intestinal tumor model that is suitable for addressing this issue, and find that hepatic

Indexed as

AnimalsAnimals, Genetically ModifiedBileCell ProliferationCholesterol 7-alpha-HydroxylaseCrosses, GeneticDisease Models, AnimalEpitheliumFemaleGene Expression RegulationInflammationIntestinal NeoplasmsIntestinesLarvaLiverMaleCholesterol 7-alpha-HydroxylaseCyp7a1 protein, zebrafishZebrafish ProteinsCholesterol metabolismcyp7a1Growth defectHepatomegalyIntestinal tumorLiver inflammation

Identifiers

PMID29592890
PMCPMC6124559
OpenAlexW2767578750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.