Evidence map›Paper›PMID 29592851›Full record

ArticleCMAJ open2018

Development of a provisional essential medicines list for children in Canada: consensus process.

Hannah Woods, Efosa Oronsaye, Anjli Bali, Yathavan Rajakulasingam, Taehoon Lee, Norman Umali, Eyal Cohen, Yaron Finkelstein, Martin Offringa, Nav Persaud

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in CMAJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Patient Safety: A Deep Concern to Caregivers.Innovations in pharmacy · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Hannah WoodsAffiliations: Centre for Urban Health Solutions (Woods, Oronsaye, Bali, Rajakulasingam, Lee, Umali, Persaud), Li Ka Shing Knowledge Institute, St. Michael's Hospital; Department of Family and Community Medicine (Persaud), University of Toronto; The Hospital for Sick Children (Cohen, Finkelstein, Offringa); University of Toronto (Cohen, Finkelstein, Offringa); Institute of Health Policy, Management and Evaluation (Cohen, Persaud), Toronto, Ont.
Efosa OronsayeAffiliations: Centre for Urban Health Solutions (Woods, Oronsaye, Bali, Rajakulasingam, Lee, Umali, Persaud), Li Ka Shing Knowledge Institute, St. Michael's Hospital; Department of Family and Community Medicine (Persaud), University of Toronto; The Hospital for Sick Children (Cohen, Finkelstein, Offringa); University of Toronto (Cohen, Finkelstein, Offringa); Institute of Health Policy, Management and Evaluation (Cohen, Persaud), Toronto, Ont.
Anjli BaliAffiliations: Centre for Urban Health Solutions (Woods, Oronsaye, Bali, Rajakulasingam, Lee, Umali, Persaud), Li Ka Shing Knowledge Institute, St. Michael's Hospital; Department of Family and Community Medicine (Persaud), University of Toronto; The Hospital for Sick Children (Cohen, Finkelstein, Offringa); University of Toronto (Cohen, Finkelstein, Offringa); Institute of Health Policy, Management and Evaluation (Cohen, Persaud), Toronto, Ont.
Yathavan RajakulasingamAffiliations: Centre for Urban Health Solutions (Woods, Oronsaye, Bali, Rajakulasingam, Lee, Umali, Persaud), Li Ka Shing Knowledge Institute, St. Michael's Hospital; Department of Family and Community Medicine (Persaud), University of Toronto; The Hospital for Sick Children (Cohen, Finkelstein, Offringa); University of Toronto (Cohen, Finkelstein, Offringa); Institute of Health Policy, Management and Evaluation (Cohen, Persaud), Toronto, Ont.
Taehoon LeeAffiliations: Centre for Urban Health Solutions (Woods, Oronsaye, Bali, Rajakulasingam, Lee, Umali, Persaud), Li Ka Shing Knowledge Institute, St. Michael's Hospital; Department of Family and Community Medicine (Persaud), University of Toronto; The Hospital for Sick Children (Cohen, Finkelstein, Offringa); University of Toronto (Cohen, Finkelstein, Offringa); Institute of Health Policy, Management and Evaluation (Cohen, Persaud), Toronto, Ont.
Norman UmaliAffiliations: Centre for Urban Health Solutions (Woods, Oronsaye, Bali, Rajakulasingam, Lee, Umali, Persaud), Li Ka Shing Knowledge Institute, St. Michael's Hospital; Department of Family and Community Medicine (Persaud), University of Toronto; The Hospital for Sick Children (Cohen, Finkelstein, Offringa); University of Toronto (Cohen, Finkelstein, Offringa); Institute of Health Policy, Management and Evaluation (Cohen, Persaud), Toronto, Ont.
Eyal CohenAffiliations: Centre for Urban Health Solutions (Woods, Oronsaye, Bali, Rajakulasingam, Lee, Umali, Persaud), Li Ka Shing Knowledge Institute, St. Michael's Hospital; Department of Family and Community Medicine (Persaud), University of Toronto; The Hospital for Sick Children (Cohen, Finkelstein, Offringa); University of Toronto (Cohen, Finkelstein, Offringa); Institute of Health Policy, Management and Evaluation (Cohen, Persaud), Toronto, Ont.
Yaron FinkelsteinAffiliations: Centre for Urban Health Solutions (Woods, Oronsaye, Bali, Rajakulasingam, Lee, Umali, Persaud), Li Ka Shing Knowledge Institute, St. Michael's Hospital; Department of Family and Community Medicine (Persaud), University of Toronto; The Hospital for Sick Children (Cohen, Finkelstein, Offringa); University of Toronto (Cohen, Finkelstein, Offringa); Institute of Health Policy, Management and Evaluation (Cohen, Persaud), Toronto, Ont.
Martin OffringaAffiliations: Centre for Urban Health Solutions (Woods, Oronsaye, Bali, Rajakulasingam, Lee, Umali, Persaud), Li Ka Shing Knowledge Institute, St. Michael's Hospital; Department of Family and Community Medicine (Persaud), University of Toronto; The Hospital for Sick Children (Cohen, Finkelstein, Offringa); University of Toronto (Cohen, Finkelstein, Offringa); Institute of Health Policy, Management and Evaluation (Cohen, Persaud), Toronto, Ont.
Nav PersaudAffiliations: Centre for Urban Health Solutions (Woods, Oronsaye, Bali, Rajakulasingam, Lee, Umali, Persaud), Li Ka Shing Knowledge Institute, St. Michael's Hospital; Department of Family and Community Medicine (Persaud), University of Toronto; The Hospital for Sick Children (Cohen, Finkelstein, Offringa); University of Toronto (Cohen, Finkelstein, Offringa); Institute of Health Policy, Management and Evaluation (Cohen, Persaud), Toronto, Ont.
Hospital for Sick Children · CASickKids Foundation · CASt Michaels Hospital · GBSt. Michael's Hospital · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWorldwide, many countries have developed a list of essential medicines for children to improve prescribing. We aimed to create an essential medicines list for children in Canada.

methodsWe adapted the previously created preliminary list of essential medicines for adults in Canada and the WHO Model List of Essential Medicines for Children to create a provisional list of essential medicines for children in Canada. Canadian clinicians made suggestions for changes. Literature relevant to each suggestion was presented to clinician-scientists, who used a modified nominal group technique to make recommendations on the suggestions. Ontario Public Drug Programs prescription data were reviewed to identify commonly prescribed medications missing from the list. Literature relevant to these medications was shared with a clinician-scientist review panel to determine which should be added, and a revised list was developed.

resultsA total of 76 items were removed from the list of essential medicines for adults in Canada because they were not indicated for use in children or were not relevant in the Canadian health care context; 7 medications were added to the child list based on Ontario Public Drugs Programs prescribing data and clinician-scientist review. Suggestions to add, remove or substitute medications were made by peer-reviewers and resulted in removal of 1 medication and replacement of 1 medication. The process produced a provisional list of 67 essential medications for children.

interpretationA provisional list of 67 essential medicines for children was created through a peer-reviewed, multistep process based on current clinical evidence, Canadian clinical practice guidelines and historical prescribing data. It is publicly posted at http://cleanmeds.ca/. The list should be further developed based on wider input and should be continuously revised based on emerging evidence of the safety and effectiveness of these medicines in all pediatric age groups.

Identifiers

PMID29592851
PMCPMC5878944
OpenAlexW2794614376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.