Evidence map›Paper›PMID 29590638›Full record

ArticleDisease models & mechanisms2018

Feeding difficulties, a key feature of the

Sarah Foriel, Julien Beyrath, Ilse Eidhof, Richard J Rodenburg, Annette Schenck, Jan A M Smeitink

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Leigh Syndrome: A Tale of Two Genomes.Frontiers in physiology · 2021
    Review
  8. Insights from Drosophila on mitochondrial complex I.Cellular and molecular life sciences : CMLS · 2020
    Review
  9. Article
  10. AFrontiers in genetics · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sarah ForielKhondrion BV, Philips van Leydenlaan 15, 6525 EX, Nijmegen, The Netherlands.
Julien BeyrathKhondrion BV, Philips van Leydenlaan 15, 6525 EX, Nijmegen, The Netherlands.ORCID 0000-0003-4181-1216
Ilse EidhofDepartment of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA, Nijmegen, The Netherlands.
Richard J RodenburgRadboud Center for Mitochondrial Medicine (RCMM) at the Department of Pediatrics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6500 HB, Nijmegen, The Netherlands.ORCID 0000-0001-5227-3527
Annette SchenckDepartment of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA, Nijmegen, The Netherlands Annette.Schenck@radboudumc.nl Jan.Smeitink@radboudumc.nl.ORCID 0000-0002-6918-3314
Jan A M SmeitinkKhondrion BV, Philips van Leydenlaan 15, 6525 EX, Nijmegen, The Netherlands Annette.Schenck@radboudumc.nl Jan.Smeitink@radboudumc.nl.ORCID 0000-0003-1392-8038
Radboud University Nijmegen · NLKhondrion (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial diseases are associated with a wide variety of clinical symptoms and variable degrees of severity. Patients with such diseases generally have a poor prognosis and often an early fatal disease outcome. With an incidence of 1 in 5000 live births and no curative treatments available, relevant animal models to evaluate new therapeutic regimes for mitochondrial diseases are urgently needed. By knocking down ND-18, the unique

Indexed as

Feeding BehaviorAnimalsBrainDisease Models, AnimalDrosophila melanogasterDrosophila ProteinsFat BodyGene Knockdown TechniquesMitochondriaMitochondrial DiseasesMotor ActivityMusclesNeuronsOrgan SpecificityReproducibility of ResultsDrosophila ProteinsDisease modelDrosophila modelFeeding impairmentMitochondrial disease

Identifiers

PMID29590638
PMCPMC5897729
OpenAlexW2789557838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.