Evidence map›Paper›PMID 29589326›Full record

ArticleBrain imaging and behavior2019

Robust multi-label transfer feature learning for early diagnosis of Alzheimer's disease.

Bo Cheng, Mingxia Liu, Daoqiang Zhang, Dinggang Shen, Alzheimer’s Disease Neuroimaging Initiative

Abstract readEvaluation Study
In one paragraph

Article in Brain imaging and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  7. Fast Image-Level MRI Harmonization via Spectrum Analysis.Machine learning in medical imaging. MLMI (Workshop) · 2022
    Article
  8. Review
  9. Multi-auxiliary domain transfer learning for diagnosis of MCI conversion.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bo ChengKey Laboratory of Intelligent Information Processing and Control of Chongqing Municipal Institutions of Higher Education, Chongqing Three Gorges University, Chongqing, 404100, China.
Mingxia LiuDepartment of Radiology and BRIC, University of North Carolina, Chapel Hill, NC, 27599, USA.
Daoqiang ZhangDepartment of Computer Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016, China. dqzhang@nuaa.edu.cn.
Dinggang ShenDepartment of Radiology and BRIC, University of North Carolina, Chapel Hill, NC, 27599, USA. dgshen@med.unc.edu.
Alzheimer’s Disease Neuroimaging Initiative

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
Quantifying Brain Abnormality by Multimodality Neuroimage Analysis,R01AG041721 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, MINGXIA · 2012 to 2019
$3.0M
Analyzing Large-Scale Neuroimaging Data in Alzheimer's DiseaseRF1AG053867 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2016
$2.5M
Imaging Genomics Based Brain Disease PredictionR01AG049371 · NIA · UNIVERSITY OF TEXAS ARLINGTON · PI HUANG, HENG · 2015 to 2019
$2.0M
Assessing Large-scale Brain Connectivities in Mild Cognitive ImpairmentR01AG042599 · NIA · UNIVERSITY OF GEORGIA · PI LIU, TIANMING · 2013 to 2017
$1.4M
National Natural Science Foundation of China 61602072NIA NIH HHS R01 AG041721NIA NIH HHS R01 AG042599NIA NIH HHS R01 AG049371NIA NIH HHS RF1 AG053867NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

Transfer learning has been successfully used in the early diagnosis of Alzheimer's disease (AD). In these methods, data from one single or multiple related source domain(s) are employed to aid the learning task in the target domain. However, most of the existing methods utilize data from all source domains, ignoring the fact that unrelated source domains may degrade the learning performance. Also, previous studies assume that class labels for all subjects are reliable, without considering the ambiguity of class labels caused by slight differences between early AD patients and normal control subjects. To address these issues, we propose to transform the original binary class label of a particular subject into a multi-bit label coding vector with the aid of multiple source domains. We further develop a robust multi-label transfer feature learning (rMLTFL) model to simultaneously capture a common set of features from different domains (including the target domain and all source domains) and to identify the unrelated source domains. We evaluate our method on 406 subjects from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database with baseline magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) data. The experimental results show that the proposed rMLTFL method can effectively improve the performance of AD diagnosis, compared with several state-of-the-art methods.

Indexed as

Alzheimer DiseaseBiomarkersBrainCognitive DysfunctionCohort StudiesDiagnosis, Computer-AssistedEarly DiagnosisHumansMachine LearningMagnetic Resonance ImagingPattern Recognition, AutomatedSensitivity and SpecificityBiomarkersAlzheimer’s disease (AD)Feature learningMulti-label learningTransfer learning

Identifiers

PMID29589326
PMCPMC8162712

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.