Evidence map›Paper›PMID 29589290›Full record

ArticleJournal of neurovirology2018

HTLV-1 proviral load in cerebrospinal fluid may not be a good marker to differentiate asymptomatic carriers with high proviral load in blood from HAM/TSP patients.

Marina Lobato Martins, Anna Bárbara de Freitas Carneiro-Proietti, Rodrigo Nicolato, Débora Marques de Miranda, Luiz Cláudio Ferreira Romanelli

Abstract read
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In one paragraph

Article in Journal of neurovirology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Clinical Characteristics of Parkinsonism in HTLV-1-Associated Myelopathy.Annals of clinical and translational neurology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marina Lobato MartinsServiço de Pesquisa, Fundação Centro de Hematologia e Hemoterapia de Minas Gerais, Fundação HEMOMINAS, Alameda Ezequiel Dias, 321, Bairro Santa Efigênia, Belo Horizonte, Minas Gerais, 30130-110, Brazil. marina.martins@hemominas.mg.gov.br.
Anna Bárbara de Freitas Carneiro-ProiettiServiço de Pesquisa, Fundação Centro de Hematologia e Hemoterapia de Minas Gerais, Fundação HEMOMINAS, Alameda Ezequiel Dias, 321, Bairro Santa Efigênia, Belo Horizonte, Minas Gerais, 30130-110, Brazil.
Rodrigo NicolatoInstituto Nacional de Ciência e Tecnologia em Medicina Molecular, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Débora Marques de MirandaDepartamento de Pediatria, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Luiz Cláudio Ferreira RomanelliServiço de Pesquisa, Fundação Centro de Hematologia e Hemoterapia de Minas Gerais, Fundação HEMOMINAS, Alameda Ezequiel Dias, 321, Bairro Santa Efigênia, Belo Horizonte, Minas Gerais, 30130-110, Brazil.
Fundação Centro de Hematologia e Hemoterapia de Minas Gerais · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An elevated human T cell leukemia virus type 1 (HTLV-1) proviral load (PVL) is an important risk factor for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), although there is a considerable frequency of asymptomatic carriers (AC) with high PVL in blood. Our objective was to evaluate whether PVL quantified in cerebrospinal fluid (CSF) is helpful to distinguish AC from HAM when AC have high PVL in blood (AC

Indexed as

AgedCarrier StateFemaleHumansHuman T-lymphotropic virus 1MaleMiddle AgedParaparesis, Tropical SpasticProvirusesViral LoadCerebrospinal fluidHAM/TSPHTLV-1Proviral loadRisk marker

Identifiers

PMID29589290
OpenAlexW2795039469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.