Evidence map›Paper›PMID 29589132›Full record

SynthesisClinical rheumatology2018

Smoking quantity determines disease activity and function in Chinese patients with ankylosing spondylitis.

Hui Zhang, Wei Wan, Jing Liu, Shengming Dai, Yaohong Zou, Qiaoxia Qian, Yue Ding, Xia Xu, Hengdong Ji, Hongjun He and 23 more

Abstract readMeta-AnalysisMulticenter Study
PubMed Publisher
In one paragraph

Synthesis in Clinical rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Hui ZhangState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Wei WanDivision of Rheumatology and Immunology, Changhai Hospital, Shanghai, China.
Jing LiuState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Shengming DaiDepartment of Rheumatology & Immunology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Yaohong ZouDivision of Rheumatology and Immunology, Wuxi People's Hospital, Wuxi, Jiangsu Province, China.
Qiaoxia QianState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Yue DingState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Xia XuDivision of Rheumatology and Immunology, Changhai Hospital, Shanghai, China.
Hengdong JiDivision of Rheumatology, Taizhou People's Hospital, Taizhou, Jiangsu Province, China.
Hongjun HeDivision of Rheumatology, Taixing People's Hospital, Taizhou, Jiangsu Province, China.
Qi ZhuInstitute of Arthritis Research, Shanghai Academy of Chinese Medical Sciences, Guanghua Integrative Medicine Hospital, Shanghai, China.
Chengde YangDivision of Rheumatology, Ruijin Hospital, Shanghai Jiaotong University Schools of Medicine, Shanghai, China.
Shuang YeDivision of Rheumatology, Renji Hospital, Shanghai Jiaotong University Schools of Medicine, Shanghai, China.
Lindi JiangDepartment of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, China.
Jianping TangDivision of Rheumatology and Immunology, Tongji Hospital of Tongji University School of Medicine, Shanghai, China.
Qiang TongDepartment of Rheumatology & Immunology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Dongyi HeInstitute of Arthritis Research, Shanghai Academy of Chinese Medical Sciences, Guanghua Integrative Medicine Hospital, Shanghai, China.
Dongbao ZhaoDivision of Rheumatology and Immunology, Changhai Hospital, Shanghai, China.
Yuan LiState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Yanyun MaState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Jingru ZhouState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Zhendong MeiState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Xiangxiang ChenState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Ziyu YuanFudan-Taizhou Institute of Health Sciences, Taizhou, Jiangsu Province, China.
Juan ZhangFudan-Taizhou Institute of Health Sciences, Taizhou, Jiangsu Province, China.
Xiaofeng WangState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Yajun YangState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Li JinState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.
Ying GaoKey Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Xiaodong ZhouUniversity of Texas Health Science Center at Houston, Houston, TX, USA.
John D ReveilleUniversity of Texas Health Science Center at Houston, Houston, TX, USA.
Hejian ZouDivision of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China. hjzou@fudan.edu.cn.
Jiucun WangState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China. jcwang@fudan.edu.cn.

Funding

111 Project B13016International S&T Cooperation Program of China 2013DFA30870Ministry of Sciences and Technology 2011BAI09B00National Basic Research Program 2014CB541801National Natural Science Foundation of China 31521003US NIH NIAID U01 1U01AI090909
6 · The paper itself

Abstract

The objective of this study was to systemically and comprehensively evaluate the associations between smoking and disease outcomes in patients with ankylosing spondylitis (AS). Information on smoking, clinical features, and sociodemographic characteristics was collected by a questionnaire administered directly to the patient. Group differences were analyzed by t test or chi-square test. Logistic regression analysis was conducted with the Bath AS Disease Activity Index (BASDAI), Bath AS Functional Index (BASFI), C-reactive protein, and erythrocyte sedimentation rate as the dependent variables and different stratification of smoking duration, smoking intensity, and cumulative smoking as independent variables. In order to compare our results with previous studies, meta-analysis was performed to calculate standardized mean difference (SMD) for relationship between outcomes and smoking status. A total of 1178 AS patients were analyzed. Compared with non-smokers, the risk of having active disease (BASDAI ≥ 4) was higher in patients who smoked at least 15 years, or 15 cigarettes per day, or 15 pack-years (OR = 1.70 [1.06, 2.73], 1.75 [1.08, 2.82], and 1.97 [1.06, 3.67], respectively); and smokers had increasing risk of BASDAI ≥ 4 with increasing years of smoking, or cigarettes per day, or pack-years (p

Indexed as

Spondylitis, AnkylosingAdultAsian PeopleFemaleHumansMaleMiddle AgedRisk FactorsSeverity of Illness IndexSmokingSurveys and QuestionnairesYoung AdultAnkylosing spondylitisCumulative smoking exposureOutcomesSmoking durationSmoking intensity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.