Trial reportEuropean journal of applied physiology2018
Effects of resistance training on MRI-derived epicardial fat volume and arterial stiffness in women with obesity: a randomized pilot study.
Trial report in European journal of applied physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Association between body mass index reduction and epicardial adipose tissue changes across pharmacological and lifestyle interventions: a multilevel meta-regression analysis.Cardiovascular diabetology · 2026Pooled it
- Exercise modalities and dose for improving arterial stiffness in risk-enriched adults: a systematic review and dose-response network meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Can resistance training alone or resistance training combined with aerobic training improve arterial stiffness, endothelial function, and other vascular function indicators in adults with hypertension or overweight/obesity-related vascular risk? A systematic review and meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2026Pooled it
- Comparative effectiveness of exercise modalities and doses on carotid-femoral pulse wave velocity in adults: a systematic review and network meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2026Pooled it
- Effect of exercise on epicardial adipose tissue in adults: a systematic review and meta-analyses.Heart failure reviews · 2021Pooled it
- A 12-month structured exercise reduces epicardial adipose volume in a frequency-dependent manner and lowers serum M-CSF in community-dwelling older adults: a randomized controlled trial.Frontiers in public health · 2026Trial
- Vigorous-intensity exercise as a modulator of cardiac adipose tissue in women with obesity: a cross-sectional and randomized pilot study.Frontiers in endocrinology · 2023Trial
- Effect of Aerobic and Resistance Exercise on Cardiac Adipose Tissues: Secondary Analyses From a Randomized Clinical Trial.JAMA cardiology · 2019Trial
- Pharmacological and Non-Pharmacological Interventions in Diabetes Mellitus: Effects on Epicardial Adipose Tissue.International journal of molecular sciences · 2025Review
- Comparative effectiveness of exercise interventions on arterial stiffness in individuals at risk for cardiovascular disease: a systematic review and network meta-analysis.Frontiers in cardiovascular medicine · 2025Article
- Review
- Effect of Exercise Training on Arterial Stiffness in Overweight or Obese Populations.International journal of sports medicine · 2022Article
- Effects of aerobic, resistance, and combined training on endothelial function and arterial stiffness in older adults: study protocol for a systematic review and meta-analysis.Systematic reviews · 2022Article
- Epicardial Adipose Tissue: A Novel Potential Imaging Marker of Comorbidities Caused by Chronic Inflammation.Nutrients · 2022Review
- Review
- Review
- Physical Exercise Potentially Targets Epicardial Adipose Tissue to Reduce Cardiovascular Disease Risk in Patients with Metabolic Diseases: Oxidative Stress and Inflammation Emerge as Major Therapeutic Targets.Antioxidants (Basel, Switzerland) · 2021Review
- Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association.Circulation · 2021Review
- Cardiac Adiposity and Arrhythmias: The Role of Imaging.Diagnostics (Basel, Switzerland) · 2021Review
- Cardiometabolic-Based Chronic Disease, Addressing Knowledge and Clinical Practice Gaps: JACC State-of-the-Art Review.Journal of the American College of Cardiology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo date, few studies have analyzed the effects of exercise on cardiac adipose tissue. Overall, exercise programs did not meet the recommendations for significant weight loss, the utilization of resistance training was minimal, and the conclusions derived from these studies have diminished exercise as a strategy for cardiac fat loss. PURPOSE: The objective of this pilot study was to analyze the effects of 3-week high-intensity, moderate-volume muscular endurance resistance training (RT) on cardiac fat and arterial stiffness.
methodsA total of 11 young females with obesity, BMI = 34.13 (± 3.16) kg/m
resultsEAT and PAT volumes (ml) showed significant interaction effects (p = 0.037 and p = 0.031), and very large changes (d > 1) of EAT (p = 0.006) and PAT (p = 0.036) in the intervention group. In addition, strength was significantly improved, including BP (p = 0.003), LP (p = 0.001), BP-to-BW ratio (p = 0.001), and LP-to-BW ratio (p = 0.002), while no changes were found in PWV.
conclusionsHigh-intensity, moderate-volume RT, designed to enhance muscular endurance following the recommendations reduces EAT and PAT volumes, improves physical fitness in females with obesity, and has no negative effects on arterial stiffness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.