Evidence map›Paper›PMID 29589060›Full record

ArticleCalcified tissue international2018

Associations Between Objectively Measured Physical Activity, Body Composition and Sarcopenia: Findings from the Hertfordshire Sarcopenia Study (HSS).

Leo D Westbury, Richard M Dodds, Holly E Syddall, Alicja M Baczynska, Sarah C Shaw, Elaine M Dennison, Helen C Roberts, Avan Aihie Sayer, Cyrus Cooper, Harnish P Patel

Open access · hybridAbstract read
In one paragraph

Article in Calcified tissue international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. The relationship between sarcopenia and fragility fracture-a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Pooled it
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  11. Exploring the complex associations among risks of malnutrition, sarcopenia, and frailty in community-dwelling older adults.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2024
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  16. The serum small non-coding RNA (SncRNA) landscape as a molecular biomarker of age associated muscle dysregulation and insulin resistance in older adults.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Leo D WestburyMRC Lifecourse Epidemiology Unit, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD, UK.
Richard M DoddsAcademic Geriatric Medicine, University of Southampton, Southampton, UK.
Holly E SyddallMRC Lifecourse Epidemiology Unit, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD, UK.
Alicja M BaczynskaAcademic Geriatric Medicine, University of Southampton, Southampton, UK.
Sarah C ShawMRC Lifecourse Epidemiology Unit, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD, UK.
Elaine M DennisonMRC Lifecourse Epidemiology Unit, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD, UK.
Helen C RobertsAcademic Geriatric Medicine, University of Southampton, Southampton, UK.
Avan Aihie SayerAcademic Geriatric Medicine, University of Southampton, Southampton, UK.
Cyrus CooperMRC Lifecourse Epidemiology Unit, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD, UK.
Harnish P PatelMRC Lifecourse Epidemiology Unit, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD, UK. hp@mrc.soton.ac.uk.ORCID 0000-0002-0081-1802
University Hospital Southampton NHS Foundation Trust · GBThe Neurosciences Foundation · GBUniversity of Southampton · GB

Funding

Department of HealthMedical Research Council G0400491Medical Research Council MC_U147574212Medical Research Council MC_U147574234Medical Research Council MC_U147574237Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UU_12011/1
6 · The paper itself

Abstract

Regular physical activity (PA) is associated with reduced risk of the development and progression of musculoskeletal, metabolic and vascular disease. However, PA declines with age and this can contribute to multiple adverse outcomes. The aims of this study were to describe the relationship between accelerometer-determined PA, body composition and sarcopenia (the loss of muscle mass and function with age). Seven-day PA was measured using the GENEactiv accelerometer among 32 men and 99 women aged 74-84 years who participated in the Hertfordshire Sarcopenia Study. We measured mean daily acceleration and minutes/day spent in non-sedentary and moderate-to-vigorous physical activity (MVPA) levels. Body composition was measured by dual-energy X-ray absorptiometry, muscle strength by grip dynamometry and function by gait speed. Sarcopenia was defined according to the EWGSOP diagnostic algorithm. Men and women spent a median (inter-quartile range) of 138.8 (82, 217) and 186 (122, 240) minutes/day engaging in non-sedentary activity but only 14.3 (1.8, 30.2) and 9.5 (2.1, 18.6) min in MVPA, respectively. Higher levels of PA were associated with reduced adiposity, faster walking speed and decreased risk of sarcopenia. For example, a standard deviation (SD) increase in mean daily acceleration was associated with an increase in walking speed of 0.25 (95% CI 0.05, 0.45) SDs and a reduction in the risk of sarcopenia of 35% (95% CI 1, 57%) in fully adjusted analyses. PA was not associated with hand grip strength. Community-dwelling older adults in this study were largely sedentary but there was evidence that higher levels of activity were associated with reduced adiposity and improved function. PA at all intensity levels in later life may help maintain physical function and protect against sarcopenia.

Indexed as

AdiposityAgedAged, 80 and overBody CompositionExerciseFemaleHand StrengthHumansMaleSarcopeniaWalking SpeedAccelerometerBody compositionObjectively measured physical activityPhysical performanceSarcopenia

Identifiers

PMID29589060
PMCPMC6049619
OpenAlexW2794547640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.