Evidence map›Paper›PMID 29588927›Full record

ArticleEpilepsia open2016

Classification of the epilepsies: New concepts for discussion and debate-Special report of the ILAE Classification Task Force of the Commission for Classification and Terminology.

Ingrid E Scheffer, Jacqueline French, Edouard Hirsch, Satish Jain, Gary W Mathern, Solomon L Moshé, Emilio Perucca, Torbjorn Tomson, Samuel Wiebe, Yue-Hua Zhang and 1 more

Abstract read
In one paragraph

Article in Epilepsia open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Clonazepam monotherapy for treating people with newly diagnosed epilepsy.The Cochrane database of systematic reviews · 2022
    Pooled it
  4. Pooled it
  5. Clonazepam monotherapy for treating people with newly diagnosed epilepsy.The Cochrane database of systematic reviews · 2019
    Pooled it
  6. Management of epilepsy in brain tumors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019
    Guideline
  7. Article
  8. Review
  9. Article
  10. Study of Eye Movements Abnormalities in Epilepsy.Neuro-ophthalmology (Aeolus Press) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Identification of a novelFrontiers in genetics · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ingrid E SchefferDepartments of Medicine and Paediatrics The University of Melbourne and Florey Institute Melbourne Victoria Australia.
Jacqueline FrenchDepartment of Neurology Langone School of Medicine New York University New York New York U.S.A.
Edouard HirschUniversity-Hospital-INSERM U 964 Strasbourg France.
Satish JainIndian Epilepsy Centre New Delhi India.
Gary W MathernDepartments of Neurosurgery, Psychiatry and Biobehavioral Medicine David Geffen School of Medicine UCLA Los Angeles California U.S.A.
Solomon L MoshéDepartment of Neurology Department of Neuroscience and Department of Pediatrics Albert Einstein College of Medicine and Montefiore Medical Center Bronx New York U.S.A.
Emilio PeruccaInstitute of Neurology IRCCS C. Mondino Foundation and Clinical Pharmacology Unit University of Pavia Pavia Italy.
Torbjorn TomsonDepartment of Clinical Neuroscience Karolinska Institute Stockholm Sweden.
Samuel WiebeDepartments of Clinical Neurosciences and Community Health Sciences University of Calgary Calgary Alberta Canada.
Yue-Hua ZhangDepartment of Pediatrics Peking University First Hospital Beijing China.
Sameer M ZuberiPaediatric Neurosciences Research Group Fraser of Allander Neurosciences Unit Royal Hospital for Children Glasgow United Kingdom.

Funding

Consequences of Prolonged Febrile Seizures in ChildhoodR01NS043209 · NINDS · MONTEFIORE MEDICAL CENTER (BRONX, NY) · PI SHINNAR, SHLOMO · 2003 to 2012
$21.5M
Consequences of Prolonged Febrile Seizures in ChildhoodR37NS043209 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SHINNAR, SHLOMO · 2013 to 2019
$11.4M
NINDS NIH HHS R01 NS043209NINDS NIH HHS R37 NS043209
6 · The paper itself

Abstract

The ILAE Task Force on Classification presents a road map for the development of an updated, relevant classification of the epilepsies. Our objective is to explain the process to date and the plan moving forward as well as to invite further discussion about the newly proposed terms and concepts. Here, we present our response to feedback about the 2010 Organization of the Epilepsies and clarify the reintroduction of the word "classification" to map out a framework for epilepsy diagnosis. We introduce some new concepts and suggest four diagnostic levels: seizure type, epilepsy category, epilepsy syndrome, and epilepsy with (specific) etiology to denote specific levels of diagnosis. We expand the etiological categories to six, focusing on those with treatment implications. Finally, we discuss the changes in terminology originally suggested and modifications in response to comments from the epilepsy community. We welcome feedback and discussion from the global epilepsy community, particularly for the new suggested terms, so that we can cement a classification that both reflects current thinking and scientific understanding and provides a dynamic, evolving framework.

Indexed as

ClassificationEpilepsy syndromesEtiologyTerminology

Identifiers

PMID29588927
PMCPMC5867836

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.