Evidence map›Paper›PMID 29588912›Full record

ArticleOpen forum infectious diseases2018

Changes Over Time in Nasopharyngeal Colonization in Children Under 2 Years of Age at the Time of Diagnosis of Acute Otitis Media (1999-2014).

Judith M Martin, Alejandro Hoberman, Nader Shaikh, Timothy Shope, S Onika Bhatnagar, Stan L Block, Mary Ann Haralam, Marcia Kurs-Lasky, Michael Green

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Judith M MartinDivisions of General Academic Pediatrics and Pediatric Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.
Alejandro HobermanDivisions of General Academic Pediatrics and Pediatric Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.
Nader ShaikhDivisions of General Academic Pediatrics and Pediatric Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.
Timothy ShopeDivisions of General Academic Pediatrics and Pediatric Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.
S Onika BhatnagarDivisions of General Academic Pediatrics and Pediatric Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.
Stan L BlockKentucky Pediatric Research, Inc., Bardstown, Kentucky.
Mary Ann HaralamDivisions of General Academic Pediatrics and Pediatric Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.
Marcia Kurs-LaskyDivisions of General Academic Pediatrics and Pediatric Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.
Michael GreenDivisions of General Academic Pediatrics and Pediatric Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
Efficacy of Antimicrobials in Young Children with AOMU01AI066007 · NIAID · CHILDREN'S HOSP PITTSBURGH/UPMC HLTH SYS · PI HOBERMAN, ALEJANDRO · 2006 to 2009
$2.0M
NCRR NIH HHS UL1 RR024153NIAID NIH HHS HHSN272201000047CNIAID NIH HHS HHSN272201000047INIAID NIH HHS U01 AI066007
6 · The paper itself

Abstract

backgroundIn children with acute otitis media (AOM), a decrease in nasopharyngeal (NP) colonization with vaccine serotypes of

methodsIn 4 separate studies, we obtained NP cultures from children aged 6-23 months presenting with AOM. Cohort 1 was recruited before routine use of PCV7 (1999-2000); 93% of children in cohort 2 (2003-2005) and 100% in cohort 3 (2006-2009) received ≥2 doses of PCV7. All children in cohort 4 (2012-2014) received ≥2 doses of PCV13. Isolates of

resultsA total of 899 children were evaluated. NP colonization with

conclusionsAlthough an initial increase in

Indexed as

AOMHaemophilus influenzaenasopharyngeal colonizationStreptococcus pneumoniae

Identifiers

PMID29588912
PMCPMC5842555

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.