Evidence map›Paper›PMID 29588810›Full record

ArticleWorld journal of cardiology2018

Increased frequency of angina attacks caused by switching a brand-name vasodilator to a generic vasodilator in patients with vasospastic angina: Two case reports.

Remi Goto-Semba, Yuichi Fujii, Tomohiro Ueda, Chikage Oshita, Hiroki Teragawa

Open access · hybridAbstract readCase Reports
In one paragraph

Article in World journal of cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Remi Goto-SembaDepartment of Education and Training, JR Hiroshima Hospital, Hiroshima 732-0057, Japan.
Yuichi FujiiDepartment of Cardiovascular Medicine, JR Hiroshima Hospital, Hiroshima 732-0057, Japan.
Tomohiro UedaDepartment of Cardiovascular Medicine, JR Hiroshima Hospital, Hiroshima 732-0057, Japan.
Chikage OshitaDepartment of Cardiovascular Medicine, JR Hiroshima Hospital, Hiroshima 732-0057, Japan.
Hiroki TeragawaDepartment of Cardiovascular Medicine, JR Hiroshima Hospital, Hiroshima 732-0057, Japan. hiroteraga71@gmail.com.
Hiroshima General Hospital · JPFutaba (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well known that calcium channel blockers (CCBs) are the first line of therapy for vasospastic angina (VSA). Here, we report two cases of VSA with an increase in the frequency of angina attacks after switching from a brand-name to a generic CCB. In both cases, angina recurred upon switching from a brand-name CCB to a generic CCB during follow-up. The patients' condition improved upon switching back to the original CCB. Both cases involved a high severity of VSA, based on the results of spasm provocation testing. These findings suggest that, in some patients with severe VSA, the frequency of angina attacks increases when switching from a brand-name CCB to a generic CCB. Cardiologists should consider this factor when prescribing drugs for angina.

Indexed as

AcetylcholineBrand-name drugsGeneric drugsRefractory chest painVasospastic angina

Identifiers

PMID29588810
PMCPMC5867450
OpenAlexW2792173893

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.