ArticleInterventional cardiology (London, England)2014
Fractional Flow Reserve Derived from Coronary Imaging and Computational Fluid Dynamics.
Article in Interventional cardiology (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 15 citations in OpenAlex.
- Calcific versus non-calcific plaque: a CAD-RADS and FFRCT study.The international journal of cardiovascular imaging · 2025Article
- Efficient Cardiovascular Parameters Estimation for Fluid-Structure Simulations Using Gappy Proper Orthogonal Decomposition.Annals of biomedical engineering · 2024Article
- Coronary CT angiography-based estimation of myocardial perfusion territories for coronary artery FFR and wall shear stress simulation.Scientific reports · 2021Article
- Ischemic Heart Disease: Noninvasive Imaging Techniques and Findings.Radiographics : a review publication of the Radiological Society of North America, IncArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
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Abstract
The assessment of functional severity of atherosclerotic stenoses in patients with coronary artery disease by invasive fractional flow reserve (FFR) measurement requires coronary artery cannulation, advancement of a wire and intravenous adenosine infusion with inherent procedure-related risk and costs. Coronary computed tomographic angiography (CCTA) and rotational coronary angiography (RA) have been recently used in conjunction with computational fluid dynamics (CFD) and image-based modelling for the determination of FFR without the need for additional imaging, modification of acquisition protocols or administration of medication. FFR derived from CCTA was demonstrated as superior to measures of CCTA stenosis severity for determination of lesion-specific ischaemia. Estimation of FFR from RA images and CFD provides a less invasive alternative to conventional FFR measurement while estimated values are in agreement with measured values. These new, combined anatomic-functional assessments have the potential to simplify the noninvasive diagnosis of coronary artery disease with a single study to identify patients with ischaemia-causing stenosis who may benefit from revascularisation.
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