Evidence map›Paper›PMID 29588739›Full record

ArticleInterventional cardiology (London, England)2017

Predilatation Prior to Transcatheter Aortic Valve Implantation: Is it Still a Prerequisite?

Matteo Pagnesi, Luca Baldetti, Paolo Del Sole, Antonio Mangieri, Marco B Ancona, Damiano Regazzoli, Nicola Buzzatti, Francesco Giannini, Antonio Colombo, Azeem Latib

Abstract read
In one paragraph

Article in Interventional cardiology (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Balloon Aortic Valvuloplasty Prior to Self-Expanding TAVI: The BAVSE-TAVI Registry.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Article
  4. Article
  5. Article
  6. Transcatheter aortic valve replacement from a single vascular access: an ultra-minimalist approach.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matteo PagnesiInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Luca BaldettiInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Paolo Del SoleInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Antonio MangieriInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Marco B AnconaInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Damiano RegazzoliInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Nicola BuzzattiDepartment of Cardiovascular and Thoracic Surgery, San Raffaele Scientific Institute, Milan, Italy.
Francesco GianniniInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Antonio ColomboInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Azeem LatibInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Predilatation has been historically considered a mandatory step before transcatheter aortic valve implantation (TAVI) since it facilitates valve crossing and prosthesis delivery, ensures optimal valve expansion and improves hemodynamic stability during valve deployment. However, as a result of procedural evolution over time, direct TAVI (without pre-implantation balloon aortic valvuloplasty) has emerged as an interesting option to simplify the procedure and to avoid potential valvuloplasty-related complications. Several real-world retrospective studies and one small randomised study have shown that direct TAVI (with both self-expanding and balloon-expandable prostheses) is feasible, safe and associated with outcomes similar to standard TAVI with pre-implantation balloon aortic valvuloplasty. In the absence of high-quality, robust evidence, the current review aims to discuss the advantages and disadvantages of omitting predilatation prior to TAVI.

Indexed as

aortic valve calcificationballoon aortic valvuloplastycerebral embolic riskdirect transcatheter aortic valve implantationparavalvular leakagepermanent pacemakerpostdilatationpredilatationTranscatheter aortic valve implantation

Identifiers

PMID29588739
PMCPMC5808664

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.