Evidence map›Paper›PMID 29588580›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2018

A functional SNP upstream of the

Jin-Xiu Li, Wei-Ping Fu, Jing Zhang, Xiao-Hua Zhang, Chang Sun, Lu-Ming Dai, Li Zhong, Li Yu, Ya-Ping Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Association ofOpen life sciences · 2023
    Article
  5. Role of Genetic Polymorphisms inInternational journal of chronic obstructive pulmonary disease · 2022
    Article
  6. Association betweenZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021
    Article
  7. Article
  8. Article
  9. The etiologic origins for chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2019
    Review
  10. The rs74794265 SNP of theInternational journal of chronic obstructive pulmonary disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Jin-Xiu Li *State Key Laboratory for Conservation and Utilization of Bio-Resource in Yunnan.
Wei-Ping Fu *Department of Respiratory Critical Care Medicine.
Jing ZhangDepartment of Thoracic Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming.
Xiao-Hua ZhangState Key Laboratory for Conservation and Utilization of Bio-Resource in Yunnan.
Chang SunState Key Laboratory for Conservation and Utilization of Bio-Resource in Yunnan.
Lu-Ming DaiDepartment of Respiratory Critical Care Medicine.
Li ZhongState Key Laboratory for Conservation and Utilization of Bio-Resource in Yunnan.
Li YuState Key Laboratory for Conservation and Utilization of Bio-Resource in Yunnan.
Ya-Ping ZhangState Key Laboratory for Conservation and Utilization of Bio-Resource in Yunnan.
Yunnan University · CNCulture Resource · EGSociety of Critical Care Medicine · USKunming Institute of Zoology · CNKunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous studies have suggested that β Methods: In this study, SNaPshot genotyping, luciferase assay, chromatin immunoprecipitation and real-time polymerase chain reaction were adopted to investigate the association between Results: One single nucleotide polymorphism (rs12654778), located upstream of Conclusion: Our findings suggest a previously unknown mechanism linking allele-specific effects of rs12654778 on

Indexed as

Polymorphism, Single NucleotideAdultAgedBinding SitesCase-Control StudiesCell LineChinaChi-Square DistributionFemaleForced Expiratory VolumeGene FrequencyGenetic Association StudiesGenetic Predisposition to DiseaseHumansLogistic ModelsLungADRB2 protein, humanNeurofibromin 1Receptors, Adrenergic, beta-2ADRB2FEV1lungpolymorphismβ2-adrenergic receptor

Identifiers

PMID29588580
PMCPMC5859892
OpenAlexW2789479175

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.