Evidence map›Paper›PMID 29588547›Full record

ArticleLeukemia2018

Ongoing clonal evolution in chronic myelomonocytic leukemia on hypomethylating agents: a computational perspective.

Hein Than, Yi Qiao, Xiaomeng Huang, Dongqing Yan, Jamshid S Khorashad, Anthony D Pomicter, Tibor J Kovacsovics, Gabor T Marth, Thomas O'Hare, Michael W Deininger

Open access · greenAbstract read
In one paragraph

Article in Leukemia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Contemporary CMML Risk Stratification and Management.Current hematologic malignancy reports · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 3 countries.

Hein ThanHuntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA.
Yi QiaoEccles Institute of Human Genetics, The University of Utah, Salt Lake City, UT, USA.
Xiaomeng HuangEccles Institute of Human Genetics, The University of Utah, Salt Lake City, UT, USA.
Dongqing YanHuntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA.
Jamshid S KhorashadHuntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA.
Anthony D PomicterHuntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA.
Tibor J KovacsovicsCentre for Hematology, Department of Medicine, Imperial College, London, UK.
Gabor T MarthEccles Institute of Human Genetics, The University of Utah, Salt Lake City, UT, USA.ORCID http://orcid.org/0000-0003-0222-1694
Thomas O'HareHuntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA.
Michael W DeiningerHuntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA. michael.deininger@hci.utah.edu.
University of Utah · USImperial College London · GB

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI KATHARINE S ULLMAN · 1986 to 2026
$72.6M
Robust Software Tools for Variant Identification and Functional AssessmentU01HG006513 · NHGRI · UNIVERSITY OF UTAH · PI ABECASIS, GONCALO, MARTH, GABOR T · 2012 to 2015
$4.2M
Monitoring tumor subclonal heterogeneity over time and spaceU24CA209999 · NCI · UNIVERSITY OF UTAH · PI MARTH, GABOR T, QUINLAN, AARON R · 2016 to 2020
$3.9M
Mechanisms of resistance to ponatinib therapy in chronic myeloid leukemiaR01CA178397 · NCI · UNIVERSITY OF UTAH · PI DEININGER, MICHAEL W., O'HARE, THOMAS J. · 2014 to 2018
$2.6M
Univ of Utah Cell Sorter for Flow Cytometry CoreS10RR026802 · NCRR · UNIVERSITY OF UTAH · PI GREEN, WAYNE FRANCIS · 2010 to 2010
$500k
NCI NIH HHS P30 CA042014NCI NIH HHS R01 CA178397NCI NIH HHS U24 CA209999NCRR NIH HHS S10 RR026802NHGRI NIH HHS U01 HG006513
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomarkers, TumorClonal EvolutionDecitabineDNA MethylationExome SequencingGenetic HeterogeneityGenome-Wide Association StudyHumansLeukemia, Myelomonocytic, ChronicModels, BiologicalPolymorphism, Single NucleotideBiomarkers, TumorDecitabine

Identifiers

PMID29588547
PMCPMC6128729
OpenAlexW2795043287

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.