ArticleBioscience reports2018
Homeostasis model assessment of insulin resistance in relation to the poor functional outcomes in nondiabetic patients with ischemic stroke.
Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Unraveling the Genetic Links: The Impacts of Antidiabetic Drugs on Stroke Risk.Reviews in cardiovascular medicine · 2025Article
- Association between atherogenic index of plasma and new-onset stroke in a population with cardiovascular-kidney-metabolic syndrome stages 0-3: insights from CHARLS.Cardiovascular diabetology · 2025Article
- A Nonlinear Relation between Body Mass Index and Long-Term Poststroke Functional Outcome-The Importance of Insulin Resistance, Inflammation, and Insulin-like Growth Factor-Binding Protein-1.International journal of molecular sciences · 2024Article
- Adipose tissue specific insulin resistance and prognosis of nondiabetic patients with ischemic stroke.Diabetology & metabolic syndrome · 2023Article
- Triglyceride-glucose index predicts death in patients with stroke younger than 65.Frontiers in neurology · 2023Article
- Immune-inflammatory, coagulation, adhesion, and imaging biomarkers combined in machine learning models improve the prediction of death 1 year after ischemic stroke.Clinical and experimental medicine · 2022Article
- Quantifying the Homeostatic Model Assessment of Insulin Resistance to Predict Mortality in Multi-organ Dysfunction Syndrome.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
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- Effects of FermentedJournal of nutrition and metabolism · 2021Article
- An Analysis of the Potential Relationship of Triglyceride Glucose and Body Mass Index With Stroke Prognosis.Frontiers in neurology · 2021Article
- Effects of different models of sucrose intake on the oxidative status of the uterus and ovary of rats.PloS one · 2021Article
- Insulin Resistance in Skeletal Muscle of Chronic Stroke.Brain sciences · 2020Article
- Effect of fish oil and telmisartan on dehydroepiandrosterone-induced polycystic ovarian syndrome in rats: The role of oxidative stress, transforming growth factor beta-1, and nuclear factor kappa B.Food science & nutrition · 2020Article
- Triglyceride Glucose Index and Prognosis of Patients With Ischemic Stroke.Frontiers in neurology · 2020Article
- Homeostasis model assessment of insulin resistance and outcome of ischemic stroke in non-diabetic patients - a prospective observational study.BMC neurology · 2019Observational
- Evaluation of serum retinol-binding protein-4 levels as a biomarker of poor short-term prognosis in ischemic stroke.Bioscience reports · 2018Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whether insulin resistance (IR) predicts worse functional outcome in ischemic stroke is still a matter of debate. The aim of the present study is to determine the association between IR and risk of poor outcome in 173 Chinese nondiabetic patients with acute ischemic stroke. This is a prospective, population-based cohort study. Insulin sensitivity, expressed by the homeostasis model assessment (HOMA) of insulin sensitivity (HOMA index = (fasting insulin × fasting glucose)/22.5). IR was defined by HOMA-IR index in the top quartile (Q4). Functional impairment was evaluated at discharge using the modified Rankin scale (mRS). The median (interquartile range) HOMA-IR was 2.14 (1.17-2.83), and Q4 was at least 2.83. There was a significantly positive correlation between HOMA-IR and National Institutes of Health Stroke Scale (
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