Evidence map›Paper›PMID 29588060›Full record

ReviewTrends in neurosciences2018

Light Therapy in Parkinson's Disease: Towards Mechanism-Based Protocols.

Karim Fifel, Aleksandar Videnovic

Open access · greenAbstract readReview
In one paragraph

Review in Trends in neurosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Efficacy and Safety of Light Therapy as a Home Treatment for Motor and Non-Motor Symptoms of Parkinson Disease: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Circadian Rhythms of Body Temperature and Locomotor Activity in Spontaneously Hypertensive Rats under Frequent Changes in Light Conditions.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Chronotherapies for Parkinson's disease.Progress in neurobiology · 2019
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Karim FifelDepartment of Molecular Cell Biology, Neurophysiology Unit, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands; International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan. Electronic address: fifel-k@hotmail.com.
Aleksandar VidenovicMovement Disorders Unit and Division of Sleep Medicine, Massachusetts General Hospital, Harvard Medical School, 165 Cambridge Street, Suite 600, Boston, MA 02446, USA.
Harvard University · USUniversity of Tsukuba · JP

Funding

Bright light modulation of non-motor symptoms in Parkinson's diseaseR01NS099055 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI VIDENOVIC, ALEKSANDAR · 2017 to 2021
$3.0M
NINDS NIH HHS R01 NS099055
6 · The paper itself

Abstract

A growing body of work is investigating the safety and efficacy of light in Parkinson's disease (PD). Here we discuss the potential of this emerging therapy to improve both motor and non-motor symptoms of PD. We also highlight directions for future basic, translational, and clinical research that are critical for the development of mechanism-based protocols of light therapy in PD.

Indexed as

PhototherapyAnimalsClinical ProtocolsHumansParkinson Diseasebright lightchronotherapynon-motor symptoms

Identifiers

PMID29588060
PMCPMC5924622
OpenAlexW2789820665

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.