Evidence map›Paper›PMID 29587717›Full record

ArticleBMC psychiatry2018

The prevalence of metabolic syndrome in patients receiving antipsychotics in Qatar: a cross sectional comparative study.

Samer Hammoudeh, Suhaila Ghuloum, Ziyad Mahfoud, Arij Yehya, Abdulmoneim Abdulhakam, Azza Al-Mujalli, Mahmoud Al-Zirie, Mohamed Osman Abdel Rahman, Angela Godwin, Noura Younes and 5 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Samer HammoudehDepartment of Research, Weill Cornell Medicine - Qatar, Doha, Qatar.
Suhaila GhuloumDepartment of Psychiatry, Rumailah Hospital, Hamad Medical Corporation, Doha, Qatar.
Ziyad MahfoudDepartment of Health Policy and Research, Weill Cornell Medicine - Qatar, Doha, Qatar.
Arij YehyaDepartment of Research, Weill Cornell Medicine - Qatar, Doha, Qatar.
Abdulmoneim AbdulhakamDepartment of Psychiatry, Rumailah Hospital, Hamad Medical Corporation, Doha, Qatar.
Azza Al-MujalliPrimary Health Care Corporation, Doha, Qatar.
Mahmoud Al-ZirieEndocrinology Department, Hamad General Hospital, Doha, Qatar.
Mohamed Osman Abdel RahmanDepartment of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar.
Angela GodwinDepartment of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar.
Noura YounesDepartment of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar.
Yahya HaniDepartment of Psychiatry, Rumailah Hospital, Hamad Medical Corporation, Doha, Qatar.
Dennis Mook-KanamoriDepartment of Physiology and Biophysics, Weill Cornell Medicine - Qatar, Doha, Qatar.
Marjonneke Mook-KanamoriDepartment of Physiology and Biophysics, Weill Cornell Medicine - Qatar, Doha, Qatar.
Reem El SherbinyDepartment of Research, Weill Cornell Medicine - Qatar, Doha, Qatar.
Hassen Al-AminDepartment of Psychiatry, Weill Cornell Medicine - Qatar, Education city, P.O. Box 24144, Doha, Qatar. haa2019@qatar-med.cornell.edu.
Weill Cornell Medical College in Qatar · QAHamad Medical Corporation · QAHamad General Hospital · QAPrimary Health Care · QA

Funding

Qatar National Research Fund NPRP 4-268-3-085
6 · The paper itself

Abstract

backgroundMetabolic abnormalities are common in patients maintained on antipsychotics. These abnormalities increase the risk of cardiovascular diseases and mortality in this population. The aim of this study is to assess the prevalence of metabolic syndrome (MetS) in subjects maintained on antipsychotics relative to controls in Qatar, and to assess the factors contributing to the development of MetS.

methodsA cross sectional design was used to collect data and fasting blood samples from subjects maintained on antipsychotics for at least six months (n = 112) and from a control group (n = 114). The groups were compared in regard to prevalence of MetS, and multiple regression analysis was used to determine the risk factors in each group.

resultsThe two groups (antipsychotics vs. control) were similar in regard to age (35.73 ± 10.28 vs. 35.73 ± 8.16 years) and gender ratio. The MetS was higher among the subjects on antipsychotics, but this difference did not reach statistical significance. Blood pressure (BP) was significantly higher in the antipsychotics group and BMI was the major risk factor to develop MetS in this group.

conclusionsThe prevalence of MetS in both groups is high and mostly attributed to obesity and high BP. Public health interventions are needed to address this major health problem overall. Larger studies are needed to further assess the impact of antipsychotics and mental illness on the development of MetS.

Indexed as

AdultAgedAntipsychotic AgentsBlood PressureCardiovascular DiseasesCross-Sectional StudiesFemaleHumansMaleMental DisordersMetabolic SyndromeMiddle AgedPrevalenceQatarRegression AnalysisRisk FactorsAntipsychotic AgentsAntipsychoticsArabsMental illnessMetabolic syndrome

Identifiers

PMID29587717
PMCPMC5870932
OpenAlexW2799591287

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.