Evidence map›Paper›PMID 29587655›Full record

Trial reportBMC anesthesiology2018

Impedance cardiography as tool for continuous hemodynamic monitoring during cesarean section: randomized, prospective double blind study.

Alessandro D'Ambrosio, Antonella Cotoia, Renata Beck, Potito Salatto, Lada Zibar, Gilda Cinnella

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03170427 (Impedance Cardiography as Tool for Continuous Hemodynamic Monitoring During Cesarean Section), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03170427 nacompletednot on this map

Impedance Cardiography as Tool for Continuous Hemodynamic Monitoring During Cesarean Section: Randomized, Prospective Double Blind Study

TypeinterventionalSponsorUniversity of FoggiaRan2013 to 2014Enrolled62ConditionsCesarean Section ComplicationsArmsImpedance cardiography, Sensory levels, Motor block, Sensory level
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Waveform analysis of differential graphs of reconstructed impedance cardiography from healthy individuals.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2020
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alessandro D'AmbrosioDepartment of Anesthesia, Intensive Care and Pain Therapy, University of Foggia, University Hospital Foggia, Foggia, Italy.
Antonella CotoiaDepartment of Anesthesia, Intensive Care and Pain Therapy, University of Foggia, University Hospital Foggia, Foggia, Italy. antonella.cotoia@unifg.it.ORCID 0000-0002-0154-0418
Renata BeckDepartment of Anesthesia, Intensive Care and Pain Therapy, University of Foggia, University Hospital Foggia, Foggia, Italy.
Potito SalattoDepartment of Anesthesia, Intensive Care and Pain Therapy, University of Foggia, University Hospital Foggia, Foggia, Italy.
Lada ZibarDepartment of Pathophysiology, Faculty of Medicine, University of Osijek, Osijek, Croatia.
Gilda CinnellaDepartment of Anesthesia, Intensive Care and Pain Therapy, University of Foggia, University Hospital Foggia, Foggia, Italy.
University of Foggia · ITKlinički bolnički centar Osijek · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImpedance Cardiography (ICG) is a non-invasive tool for continuous hemodynamic monitoring. Aims of our study were to assess the utility of ICG to evaluate the hemodynamic impact of 6 mg (GL6) vs 8 mg (GL8) levobupivacaine combined with fentanyl in healthy patients undergoing elective cesarean section; secondary, to compare the duration and quality of analgesia and anesthesia.

methodsSixty-two women receiving combined spinal-epidural (CSE) for elective cesarean delivery were randomly allocated to GL6 or GL8 groups. Mean arterial pressure (MAP), cardiac index (CI), systemic vascular resistance index (SVRI), heart rate (HR), stroke volume index (SVI) were recorded from Tbaseline to 31 min after CSE by ICG. Sensory and motor blocks, patients and surgeons satisfaction, neonatal data were also recorded.

resultsFifteen of 32 patients in GL6 and 15 of 30 patients in GL8 experienced hypotension at T2 vs Tbaseline (P < .001) and SVRI reduction (P = .035 and P < .001 respectively). MAP, CI and SVRI were always slightly higher in GL6 vs GL8. HR and SVI remained stable until the end of surgery in all patients. Total ephedrine requirements was higher in GL8 (P = .010). The onset and offset time of sensory and motor block were similar in both groups, but the number of patients with motor block was lower in GL6 vs GL8 (P = .001). Patients and surgeon satisfaction scores, the number of patients needed systemic rescue doses, neonatal data were similar in both groups.

conclusionsICG is a useful noninvasive tool to monitor continuously hemodynamics during cesarean section. The hemodynamic stability, the satisfying sensory block and rapid mobilization provided by low levobupivacaine dose may be particularly advantageous in obstetric patients.

trial registrationClinicalTrials.gov: NCT03170427 . Retrospectively Registered (Date of registration: May 2017).

Indexed as

Cesarean SectionAdultAnesthesia, ObstetricalAnesthetics, IntravenousAnesthetics, LocalCardiography, ImpedanceDouble-Blind MethodFemaleFentanylHemodynamic MonitoringHumansLevobupivacaineMonitoring, IntraoperativeProspective StudiesAnesthetics, IntravenousAnesthetics, LocalFentanylLevobupivacaineCesarean sectionHemodynamicsHypotensionImpedance CardiographyLevobupivacaine

Identifiers

PMID29587655
PMCPMC5870261
OpenAlexW2794897883

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.