Evidence map›Paper›PMID 29587417›Full record

ArticleInternational journal of molecular sciences2018

Role of the Hypothalamic-Pituitary-Adrenal Axis in Health and Disease.

Sharon DeMorrow

Abstract readEditorial
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Anthropogenic Underwater Noise Induces Anxiety-like Behavior in Zebrafish.Animals : an open access journal from MDPI · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Sharon DeMorrowDepartment of Medical Physiology, Texas A & M College of Medicine, Temple, TX 76504, USA. demorrow@medicine.tamhsc.edu.

Funding

Dysregulation of hypothalamic neuropeptides is associated with biliary hyperplasiaR01DK082435 · NIDDK · UNIVERSITY OF TEXAS AT AUSTIN · PI DEMORROW, SHARON · 2010 to 2020
$2.7M
The role of hypothalamic neuropeptides on biliary function during cholestasisI01BX002638 · VA · OLIN TEAGUE VETERANS CENTER · PI DEMORROW, SHARON · 2015 to 2018
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BLRD VA I01 BX002638NIDDK NIH HHS R01 DK082435
6 · The paper itself

Abstract

The Hypothalamic-Pituitary-adrenal (HPA) axis describes a complex set of positive and negative feedback influences between the hypothalamus, pituitary gland, and adrenal gland.[...].

Indexed as

Adrenal Cortex HormonesAdrenocorticotropic HormoneAnimalsCorticotropin-Releasing HormoneFeedback, PhysiologicalHumansHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemAdrenal Cortex HormonesAdrenocorticotropic HormoneCorticotropin-Releasing Hormone

Identifiers

PMID29587417
PMCPMC5979578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.