Evidence map›Paper›PMID 29587350›Full record

ArticleAntioxidants (Basel, Switzerland)2018

Polymeric Nanoparticles for Increasing Oral Bioavailability of Curcumin.

Anita Umerska, Caroline Gaucher, Felipe Oyarzun-Ampuero, Isabelle Fries-Raeth, Florence Colin, María Gabriela Villamizar-Sarmiento, Philippe Maincent, Anne Sapin-Minet

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 105 citations in OpenAlex.

  1. Article
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  6. Nanoencapsulation of vitamin BJournal of food science · 2025
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  11. Natural antibiotics against antimicrobial resistance: sources and bioinspired delivery systems.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Anita UmerskaUniversité de Lorraine, CITHEFOR, F-54000 Nancy, France. anita.umerska@univ-lorraine.fr.ORCID 0000-0002-4981-8247
Caroline GaucherUniversité de Lorraine, CITHEFOR, F-54000 Nancy, France. caroline.gaucher@univ-lorraine.fr.ORCID 0000-0002-0886-5522
Felipe Oyarzun-AmpueroDepartamento de Ciencias y Tecnología Farmacéuticas, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, 758-0150 Santiago, Chile.
Isabelle Fries-RaethUniversité de Lorraine, CITHEFOR, F-54000 Nancy, France. Isabelle.Raeth@univ-lorraine.fr.ORCID 0000-0002-9402-8164
Florence ColinUniversité de Lorraine, CITHEFOR, F-54000 Nancy, France. florence.colin88@gmail.com.
María Gabriela Villamizar-SarmientoDepartamento de Ciencias y Tecnología Farmacéuticas, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, 758-0150 Santiago, Chile.
Philippe MaincentUniversité de Lorraine, CITHEFOR, F-54000 Nancy, France. philippe.maincent@univ-lorraine.fr.
Anne Sapin-MinetUniversité de Lorraine, CITHEFOR, F-54000 Nancy, France.
Cibles thérapeutiques, formulation et expertise préclinique du médicamentUniversity of Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the promising biological and antioxidant properties of curcumin, its medical applications are limited due to poor solubility in water and low bioavailability. Polymeric nanoparticles (NPs) adapted to oral delivery may overcome these drawbacks. Properties such as particle size, zeta potential, morphology and encapsulation efficiency were assessed. Then, the possibility of storing these NPs in a solid-state form obtained by freeze-drying, in vitro curcumin dissolution and cytocompatibility towards intestinal cells were evaluated. Curcumin-loaded Eudragit

Indexed as

curcumincytocompatibilityEudragitintestinal cellsnanoparticlesPCLPLGAsingle emulsion-solvent evaporation method

Identifiers

PMID29587350
PMCPMC5946112
OpenAlexW2791169112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.