ArticlePloS one2018
Working memory, age and education: A lifespan fMRI study.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 57 citations in OpenAlex.
- Polygenic risk for schizophrenia predicting test-measured and self-reported cognitive performance in individuals without psychosis.BMC psychiatry · 2026Article
- Do cognitive reserve proxies capture a common neural signature? A systematic review and meta-analysis of task-based fMRI studies.Psychoradiology · 2026Review
- Trajectory-based identification of cognitive-performance phenotypes across adulthood from psychophysiological testing.Frontiers in aging neuroscience · 2026Article
- Using Machine Learning Methods to Predict Cognitive Age from Psychophysiological Tests.Healthcare (Basel, Switzerland) · 2025Article
- Muscle strength, EEG biomarkers, and working memory as interacting predictors of cognitive function in cognitively impaired older adults.Frontiers in aging neuroscience · 2025Article
- Theta-gamma-coupling as predictor of working memory performance in young and elderly healthy people.Molecular brain · 2024Article
- Eight brain structures mediate the age-related alterations of the working memory: forward and backward digit span tasks.Frontiers in psychology · 2024Article
- Cognitive and neural mechanisms of learning and interventions for improvement across the adult lifespan: A systematic review protocol.PloS one · 2024Article
- Functional gradients of the medial parietal cortex in a healthy cohort with family history of sporadic Alzheimer's disease.Alzheimer's research & therapy · 2023Article
- Evaluating test-retest reliability and sex-/age-related effects on temporal clustering coefficient of dynamic functional brain networks.Human brain mapping · 2023Article
- Complexity analysis of heartbeat-related signals in brain MRI time series as a potential biomarker for ageing and cognitive performance.The European physical journal. Special topics · 2023Article
- Age-related changes of whole-brain dynamics in spontaneous neuronal coactivations.Scientific reports · 2022Article
- Age-Specific Activation Patterns and Inter-Subject Similarity During Verbal Working Memory Maintenance and Cognitive Reserve.Frontiers in psychology · 2022Article
- The Association between the Binding Processes of Working Memory and Vascular Risk Profile in Adults.Brain sciences · 2021Article
- Differential Associations of White Matter Brain Age With Language-Related Mechanisms in Word-Finding Ability Across the Adult Lifespan.Frontiers in aging neuroscience · 2021Article
- What Can Neural Activity Tell Us About Cognitive Resources in Aging?Frontiers in psychology · 2021Review
- Combining HF rTMS over the Left DLPFC with Concurrent Cognitive Activity for the Offline Modulation of Working Memory in Healthy Volunteers: A Proof-of-Concept Study.Brain sciences · 2020Article
- The Role of Moderating Variables on BOLD fMRI Response During Semantic Verbal Fluency and Finger Tapping in Active and Educated Healthy Seniors.Frontiers in human neuroscience · 2020Article
- Understanding white matter structural connectivity differences between cognitively impaired and nonimpaired active professional fighters.Human brain mapping · 2019Article
- Correlates of Cognitive Load in Surrogate Decision Makers of the Critically III.Western journal of nursing research · 2019Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ageing is associated with grey matter atrophy and changes in task-related neural activations. This study investigated the effects of age and education on neural activation during a spatial working memory task in 189 participants aged between 20-80 years old, whilst controlling for grey matter density. Age was related to linear decreases in neural activation in task activated areas, and this effect was no longer significant when adjusting for education or accuracy. Age was also related to cubic increases in neural activation in non-task related areas, such as the temporal gyrus, cuneus and cerebellum when adjusting for accuracy and education. These findings support previous lifespan datasets indicating linear age-related decreases in task activation, but non-linear increases in non-task related areas during episodic memory tasks. The findings also support past studies indicating education offers a form of cognitive reserve through providing a form of neural compensation and highlights the need to consider education in ageing studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.