Evidence map›Paper›PMID 29584662›Full record

ArticleBiosensors2018

Development of a β-Lactoglobulin Sensor Based on SPR for Milk Allergens Detection.

Jon Ashley, Roberta D'Aurelio, Monika Piekarska, Jeff Temblay, Mike Pleasants, Linda Trinh, Thomas L Rodgers, Ibtisam E Tothill

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 75 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jon AshleyAdvanced Diagnostics and Sensors Group, Cranfield University, Cranfield MK43 0AL, UK. jash@nanotech.dtu.dk.ORCID 0000-0002-7062-1019
Roberta D'AurelioAdvanced Diagnostics and Sensors Group, Cranfield University, Cranfield MK43 0AL, UK. r.daurelio@cranfield.ac.uk.ORCID 0000-0002-0824-7433
Monika PiekarskaAdvanced Diagnostics and Sensors Group, Cranfield University, Cranfield MK43 0AL, UK. monika.piekarska9@gmail.com.
Jeff TemblaySafety and Environmental Assurance Centre, Colworth Science Park, Unilever plc, Sharnbrook, Bedford MK44 1LQ, UK. jeff.temblay@scienceexchange.com.
Mike PleasantsSafety and Environmental Assurance Centre, Colworth Science Park, Unilever plc, Sharnbrook, Bedford MK44 1LQ, UK. Mike.Pleasants@unilever.com.ORCID 0000-0003-4511-1583
Linda TrinhSchool of Chemical Engineering and Analytical Science, University of Manchester, Oxford Road, Manchester M13 9PL, UK. linda.trinh@manchester.ac.uk.
Thomas L RodgersSchool of Chemical Engineering and Analytical Science, University of Manchester, Oxford Road, Manchester M13 9PL, UK. Tom.Rodgers@manchester.ac.uk.ORCID 0000-0002-4025-3753
Ibtisam E TothillAdvanced Diagnostics and Sensors Group, Cranfield University, Cranfield MK43 0AL, UK. i.tothill@cranfield.ac.uk.ORCID 0000-0002-8208-6658
Cranfield University · GBUnilever (United Kingdom) · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A sensitive and label-free surface plasmon resonance (SPR) based sensor was developed in this work for the detection of milk allergens. β-lactoglobulin (BLG) protein was used as the biomarker for cow milk detection. This is to be used directly in final rinse samples of cleaning in-place (CIP) systems of food manufacturers. The affinity assay was optimised and characterised before a standard curve was performed in pure buffer conditions, giving a detection limit of 0.164 µg mL

Indexed as

AllergensAnimalsCattleLactoglobulinsMilkSurface Plasmon ResonanceAllergensLactoglobulinsallergenbiosensormilk proteinsurface plasmon resonance (SPR)β-lactoglobulin (BLG)

Identifiers

PMID29584662
PMCPMC6023029
OpenAlexW2791773653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.