Evidence map›Paper›PMID 29584588›Full record

ArticleRadiation research2018

Amelioration of Head and Neck Radiation-Induced Mucositis and Distant Marrow Suppression in Fanca

John Willis, Michael W Epperly, Renee Fisher, Xichen Zhang, Donna Shields, Wen Hou, Hong Wang, Song Li, Peter Wipf, Kalindi Parmar and 3 more

Abstract read
In one paragraph

Article in Radiation research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

John Willisa   Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213.
Michael W Epperlya   Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213.
Renee Fishera   Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213.
Xichen Zhanga   Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213.
Donna Shieldsa   Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213.
Wen Houa   Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213.
Hong Wanga   Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213.
Song Lib   Departments of Pharmaceutical Science, University of Pittsburgh, Pittsburgh, Pennsylvania 15260.
Peter Wipfc   Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260.
Kalindi Parmard   Dana Farber Cancer Institute, Boston, Massachusetts 02115.
Eva Guinand   Dana Farber Cancer Institute, Boston, Massachusetts 02115.
Justin Steinmana   Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213.
Joel S Greenbergera   Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213.
UPMC Hillman Cancer Center · USDana-Farber Cancer Institute · USUniversity of Pittsburgh · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHN C. BYRD · 1988 to 2026
$158.0M
Training and EducationU19AI068021 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GREENBERGER, JOEL S · 2005 to 2019
$44.4M
NCI NIH HHS P30 CA047904NIAID NIH HHS U19 AI068021
6 · The paper itself

Abstract

Squamous cell carcinomas of the head and neck are appearing with increased frequency in both marrow transplanted and non-transplanted Fanconi anemia (FA) patients. FA patients commonly display radiosensitivity of epithelial tissues, complicating effective radiotherapy. Fancd2

Indexed as

Administration, OralAnimalsBone MarrowCell SurvivalFanconi Anemia Complementation Group A ProteinFanconi Anemia Complementation Group G ProteinHead and Neck NeoplasmsHematopoiesisInterleukin-3MiceMitomycinMucositisNitrogen OxidesRadiation Injuries, ExperimentalRadiation-Protective AgentsRadiation ToleranceFanconi Anemia Complementation Group A ProteinFanconi Anemia Complementation Group G ProteinInterleukin-3JP4-039MitomycinNitrogen OxidesRadiation-Protective AgentsTransforming Growth Factor beta

Identifiers

PMID29584588
PMCPMC5973476
OpenAlexW2795128393

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.