Evidence map›Paper›PMID 29584453›Full record

ArticleAnnals of the American Thoracic Society2018

Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort.

Robert M Burkes, Amanda J Gassett, Agathe S Ceppe, Wayne Anderson, Wanda K O'Neal, Prescott G Woodruff, Jerry A Krishnan, R Graham Barr, MeiLan K Han, Fernando J Martinez and 12 more

Registry-linked trialAbstract read
In one paragraph

Article in Annals of the American Thoracic Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01969344 (Subpopulations and Intermediate Outcome Measures in COPD Study), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01969344 active not recruitingnot on this map

Subpopulations and Intermediate Outcome Measures in COPD Study

TypeobservationalSponsorUniversity of North Carolina, Chapel HillRan2010 to 2031Enrolled2,981ConditionsCOPD, Chronic Obstructive Pulmonary Disease, Chronic Bronchitis, Emphysema
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. RuralEuropean respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Reply to CurrowAmerican journal of respiratory and critical care medicine · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Towards precision in defining COPD exacerbations.Breathe (Sheffield, England) · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 13 institutions in 1 country.

Robert M BurkesDivision of Pulmonary Diseases and Critical Medicine, and.ORCID http://orcid.org/0000-0002-9718-9115
Amanda J GassettDepartment of Environmental and Occupational Health Sciences, School of Public Health, and.
Agathe S CeppeMarsico Lung Institute/Cystic Fibrosis Research Center, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Wayne AndersonMarsico Lung Institute/Cystic Fibrosis Research Center, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Wanda K O'NealMarsico Lung Institute/Cystic Fibrosis Research Center, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Prescott G WoodruffDivision of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine and Cardiovascular Research Institute, University of California San Francisco, School of Medicine, San Francisco, California.
Jerry A KrishnanDivision of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois, Chicago, Illinois.
R Graham BarrDepartment of Medicine, Columbia University Medical Center, New York, New York.
MeiLan K HanDivision of Pulmonary and Critical Care Medicine, University of Michigan Health System, Ann Arbor, Michigan.
Fernando J MartinezDepartment of Medicine, Weill Cornell Medical College, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, New York.
Alejandro P ComellasDivision of Pulmonary and Critical Care, University of Iowa, Iowa City, Iowa.ORCID http://orcid.org/0000-0003-1521-7520
Allison A LambertDivision of Pulmonary and Critical Care, University of Washington, Seattle, Washington.
Joel D KaufmanDepartment of Environmental and Occupational Health Sciences, School of Public Health, and.
Mark T DransfieldDivision of Pulmonary and Critical Care, University of Alabama at Birmingham, Birmingham, Alabama.
J Michael WellsDivision of Pulmonary and Critical Care, University of Alabama at Birmingham, Birmingham, Alabama.
Richard E KannerDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, Utah.
Robert PaineDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, Utah.
Eugene R BleeckerDivision of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University, Winston-Salem, North Carolina; and.
Laura M PaulinDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Nadia N HanselDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
M Bradley DrummondDivision of Pulmonary Diseases and Critical Medicine, and.ORCID http://orcid.org/0000-0002-6968-4610
Current and former investigators of the SPIROMICS sites and reading centers
University of North Carolina at Chapel Hill · USJohns Hopkins University · USPulmonary Associates · USUniversity of Alabama at Birmingham · USUniversity of Utah · USColumbia University Irving Medical Center · USMichigan Medicine · USNewYork–Presbyterian Hospital · USUniversity of California, San Francisco · USUniversity of Illinois Chicago · USUniversity of Iowa · USUniversity of Washington · USWake Forest University · US

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI ALI SHOJAIE · 1995 to 2026
$42.5M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Andrea Adamcakova-Dodd · 1990 to 2026
$40.5M
SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI DEAN BILLHEIMER · 1994 to 2026
$36.7M
SPIROMICS II: Biological underpinnings of COPD heterogeneity and progressionU01HL137880 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, PRESCOTT G · 2017 to 2021
$27.9M
TRAINING IN RESPIRATORY AND ENVIRONMENTAL MEDICINET32HL007106 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES, DOERSCHUK, CLAIRE M · 1985 to 2021
$7.3M
SPIROMICS - Air Pollution StudyR01ES023500 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N, KAUFMAN, JOEL DANIEL · 2014 to 2018
$3.2M
Cathelicidin and Vitamin D: Impact on Populations At-Risk and with COPDR01HL125432 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DRUMMOND, MICHAEL BRADLEY · 2015 to 2019
$3.1M
Indoor Air Pollution, Mucociliary Clearance, and Mucus Properties in COPDK23ES025781 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI PAULIN, LAURA MARIE · 2015 to 2019
$832k
NCATS NIH HHS UL1 TR002319NHLBI NIH HHS HHSN268200900013CNHLBI NIH HHS HHSN268200900014CNHLBI NIH HHS HHSN268200900015CNHLBI NIH HHS HHSN268200900016CNHLBI NIH HHS HHSN268200900017CNHLBI NIH HHS HHSN268200900018CNHLBI NIH HHS HHSN268200900019CNHLBI NIH HHS HHSN268200900020CNHLBI NIH HHS R01 HL125432NHLBI NIH HHS T32 HL007106NHLBI NIH HHS U01 HL137880NIEHS NIH HHS K23 ES025781NIEHS NIH HHS P30 ES005605NIEHS NIH HHS P30 ES006694NIEHS NIH HHS P30 ES007033NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES023500
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chronic obstructive pulmonary diseaseexacerbationrural health

Identifiers

PMID29584453
PMCPMC6207115
OpenAlexW2794853145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.