Evidence map›Paper›PMID 29583150›Full record

ReviewCardiovascular journal of Africa

Rheumatoid arthritis and risk of cardiovascular disease.

Pieter W Meyer, Ronald Anderson, James A Ker, Mahmood T Ally

Abstract readReview
In one paragraph

Review in Cardiovascular journal of Africa. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Pathology of Diabetes-Induced Immune Dysfunction.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Macrophage Dysfunction in Autoimmune Rheumatic Diseases and Atherosclerosis.International journal of molecular sciences · 2022
    Review
  18. Review
  19. The Effect of TNF-Cardiology research and practice · 2022
    Review
  20. Orchiectomy but not adjuvant-induced arthritis induces structural modifications in rat aortas.Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pieter W MeyerDepartment of Immunology, Faculty of Health Sciences, University of Pretoria, and Tshwane Academic Division of the National Health Laboratory Service of South Africa, Pretoria, South Africa. Email: Pieter.Meyer@up.ac.za.
Ronald AndersonDepartment of Immunology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
James A KerDepartment of Internal Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Mahmood T AllyDivision of Rheumatology, Department of Internal Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In developing countries, rheumatoid arthritis (RA) remains a seriously under-prioritised disease, particularly among the underprivileged, often resulting in presentation of patients late in the course of their disease, further complicated by limited therapeutic options and inconsistent follow up. The consequences are often severe with irreversible disability, increased frequency of co-morbidities, especially cardiovascular disease (CVD), and higher mortality rates, relative to developed countries. Despite addressing traditional cardiovascular risk factors, the impact of subclinical or 'residual' inflammation from uncontrolled RA needs to be considered. This narrative review explores the prevalence and pathogenesis of CVD in RA, including the impact of tobacco use. It discusses pitfalls in the risk assessment of CVD in patients with RA, and the effect of disease-modifying anti-rheumatic therapy on cardiovascular co-morbidity.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidCardiovascular DiseasesCause of DeathComorbidityDisability EvaluationHumansPrevalencePrognosisRisk AssessmentRisk FactorsSmokingTobacco, SmokelessAntirheumatic Agents

Identifiers

PMID29583150
PMCPMC8962697

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.