Evidence map›Paper›PMID 29583085›Full record

ArticleStem cells and development2018

Functional Heterogeneity of Endothelial Cells Derived from Human Pluripotent Stem Cells.

Saritha S D'Souza, Akhilesh Kumar, Igor I Slukvin

Abstract read
In one paragraph

Article in Stem cells and development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Integrated Multiparametric High-Content Profiling of Endothelial Cells.SLAS discovery : advancing life sciences R & D · 2019
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Saritha S D'Souza1 Wisconsin National Primate Research Center, University of Wisconsin , Madison, Wisconsin.
Akhilesh Kumar1 Wisconsin National Primate Research Center, University of Wisconsin , Madison, Wisconsin.
Igor I Slukvin1 Wisconsin National Primate Research Center, University of Wisconsin , Madison, Wisconsin.

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
ZOLEDRONATE PREVENTS BONE LOSS IN OVARIECTOMIZED RHESUS MONKEYSP51RR000167 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI WATKINS, DAVID I · 1985 to 2011
$106.7M
Midwest Progenitor Cell ConsortiumU01HL099773 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI THOMSON, JAMES ALEXANDER · 2009 to 2015
$7.8M
Transplantation of MHC Homozygous Vascular Progenitors in PrimatesU01HL134655 · NHLBI · MORGRIDGE INSTITUTE FOR RESEARCH, INC. · PI SLUKVIN, IGOR I. · 2016 to 2022
$7.7M
NCRR NIH HHS P51 RR000167NHLBI NIH HHS U01 HL099773NHLBI NIH HHS U01 HL134655NIH HHS P51 OD011106
6 · The paper itself

Abstract

Specification of endothelial cells (ECs) into arterial, venous, and lymphatic cells is a crucial process of vascular development, and expanding our knowledge about EC specification from human pluripotent stem cells (hPSCs) will aid the design of optimal strategies for producing desired types of ECs for therapies. In our prior studies, we revealed that hPSC-derived VE-cadherin(V)

Indexed as

Neovascularization, PhysiologicAntigens, CDAntigens, CD34BiomarkersCadherin 5CadherinsCell DifferentiationCell LineCell LineageCell MovementCell ProliferationColony-Forming Units AssayCytokinesGene ExpressionHemangioblastsHumansAntigens, CDAntigens, CD34BiomarkersCadherin 5CadherinsCytokinesLeukosialinNitric Oxide Synthase Type IIINOS3 protein, humanPlatelet Endothelial Cell Adhesion Molecule-1SPN protein, humanendothelial cellshemogenic endotheliumheterogeneityhuman pluripotent stem cells

Identifiers

PMID29583085
PMCPMC5910050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.