ArticleAsian Pacific journal of cancer prevention : APJCP2018
Possible Synergistic Interactions Among Multiple HPV Genotypes in Women Suffering from Genital Neoplasia
Article in Asian Pacific journal of cancer prevention : APJCP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Prevalence and distribution of human papillomavirus genotypes in cervical intraepithelial neoplasia in China: a meta-analysis.Archives of gynecology and obstetrics · 2020Pooled it
- The histologic results in multiple-type HPV infections.Journal of the Turkish German Gynecological Association · 2025Article
- Prevalence of Carcinogenic Genotypes of HPV-Infected Women in a Ten-Year Period (2014-2023) in Vojvodina, Serbia.Medicina (Kaunas, Lithuania) · 2024Article
- The possible impact of novel mutations in human papillomavirus 52 on the infection characteristics.Microbial genomics · 2023Article
- HPV genotyping of cervical histologic specimens of 61, 422 patients from the largest women hospital in China.Frontiers in oncology · 2023Article
- Trends in cocirculation of oncogenic HPV genotypes in single and multiple infections among the unvaccinated community.Journal of medical virology · 2022Article
- Analysis of Distributions of HPV Infection in Females with Cervical Lesions in the Western District of Beijing Chaoyang Hospital.Journal of healthcare engineering · 2022Article
- HPV testing in Iranian men: An epidemiological update.Journal of family medicine and primary care · 2021Article
- Investigation of the association between ten pathogens causing sexually transmitted diseases and high-risk human papilloma virus infection in Shanghai.Molecular and clinical oncology · 2021Article
- Frequent high-risk HPV co-infections excluding types 16 or 18 in cervical neoplasia in Guadeloupe.BMC cancer · 2021Observational
- Article
- The Impact of MTHFR 1298 A > C and 677 C > T Gene Polymorphisms as Susceptibility Risk Factors in Cervical Intraepithelial Neoplasia Related to HPV and Sexually Transmitted Infections.Journal of obstetrics and gynaecology of India · 2020Article
- Glutathione S-transferase omega gene polymorphism as a biomarker for human papilloma virus and cervical cancer in Iranian womenJournal of the Turkish German Gynecological Association · 2018Article
- Characterization of JAK2 V617F (1849 G > T) Mutation in Cervical Cancer Related to Human Papillomavirus and Sexually Transmitted Infections.Journal of cancer prevention · 2018Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Persistence of HPV infection is the true cause of cervical disorders. It is reported that competition may exist among HPV genotypes for colonization. This survey was designed to establish the multiple HPV genotype status in our community and the probability of multiple HPV infections involvement. Methods: All multiple HPV infections were selected for investigation in women suffering from genital infections referred to private laboratories in Tehran, Iran. A total of 160 multi HPV positive specimens from cervical scraping were identified by the HPV genotyping methods, "INNO-LiPA and Geno Array". Result: In present study, HPV 6 (LR), 16 (HR), 53 (pHR), 31 (HR) and 11 (LR) were included in 48.8% of detected infections as the most five dominant genotypes. HPV 16 was detected at the highest rate with genotypes 53, 31 and 52, while HPV 53 appeared linked with HPV 16, 51 and 56 in concurrent infections. It appears that HPV 16 and 53 may have significant tendencies to associate with each other rather than with other genotypes. Analysis of the data revealed there may be some synergistic interactions with a few particular genotypes such as "HPV 53". Conclusion: Multiple HPV genotypes appear more likely to be linked with development of cervical abnormalities especially in patients with genital infections. Since, there are various patterns of dominant HPV genotypes in different regions of world, more investigations of this type should be performed for careHPV programs in individual countries.
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