Evidence map›Paper›PMID 29582539›Full record

ArticleGeriatrics & gerontology international2018

Association between atherosclerosis and handgrip strength in non-hypertensive populations in India and Japan.

Hirotomo Yamanashi, Bharati Kulkarni, Tansy Edwards, Sanjay Kinra, Jun Koyamatsu, Mako Nagayoshi, Yuji Shimizu, Takahiro Maeda, Sharon E Cox

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Geriatrics & gerontology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 50 citations in OpenAlex.

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  10. Role of Endothelial Progenitor Cells in Frailty.International journal of molecular sciences · 2023
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Hirotomo YamanashiDepartment of Island and Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Goto, Japan.ORCID http://orcid.org/0000-0002-8655-4519
Bharati KulkarniClinical Division, National Institute of Nutrition, Hyderabad, India.
Tansy EdwardsTropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK.
Sanjay KinraClinical Division, National Institute of Nutrition, Hyderabad, India.
Jun KoyamatsuDepartment of Island and Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Goto, Japan.
Mako NagayoshiDepartment of Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Yuji ShimizuDepartment of Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Takahiro MaedaDepartment of Island and Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Goto, Japan.
Sharon E CoxSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
Nagasaki University · JPLondon School of Hygiene & Tropical Medicine · GBNational Institute of Nutrition · IN

Funding

Medical Research Council MR/K012126/1
6 · The paper itself

Abstract

aimAlthough several risk factors contribute to the development of sarcopenia, whether preclinical atherosclerosis contributes to the risk of sarcopenia is not established. The present cross-sectional study aimed to investigate if there is an association between preclinical atherosclerosis and muscle strength among two ethnic populations.

methodsParticipants included individuals aged ≥40 years and enrolled in the third follow-up examination of the Andhra Pradesh Children and Parents Study, India, and in the baseline assessments of the Nagasaki Islands Study, Japan. Preclinical atherosclerosis was evaluated by carotid intima-media thickness, brachial-ankle pulse wave velocity, cardio-ankle vascular index. The association of carotid intima-media thickness and pulse wave velocity/cardio-ankle vascular index with handgrip strength (HGS) was analyzed separately in the sexes and for hypertensive status from the two cohorts using a multivariable linear regression model.

resultsData on a total of 1501 participants in India and 3136 participants in Japan were analyzed. Carotid intima-media thickness was negatively associated with HGS in non-hypertensive Indian men (B coefficient = -5.38, P = 0.036). Arterial stiffness was also associated with HGS in non-hypertensive Indian men (B = -0.97, P = 0.001), but not in hypertensive Indian men. Same as Indian men, we found the significant associations between arterial stiffness and HGS in non-hypertensive women in both India and Japan (B = -0.44, P = 0.020, B = -0.63, P = 0.016, respectively), but not in hypertensive women.

conclusionsThe negative association between preclinical atherosclerosis and HGS was dominantly found in non-hypertensive participants. Geriatr Gerontol Int 2018; 18: 1071-1078.

Indexed as

AdultAgedAge FactorsAnkle Brachial IndexAtherosclerosisBlood PressureCross-Sectional StudiesFemaleHand StrengthHumansHypertensionIndiaJapanLinear ModelsMaleMiddle Agedatherosclerosiscarotid intima-media thicknesshandgrip strengthpulse wave velocitysarcopenia

Identifiers

PMID29582539
PMCPMC6144064
OpenAlexW2794654412

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.